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Articles in Press
8/7/2019 9:37:58 AM | Browse: 405 | Download: 86
| Publication Name |
World Journal of Gastroenterology |
| Manuscript ID |
48524 |
| Country of Manuscript Source |
South Korea |
| Specialty |
Gastroenterology and Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Value of controlled attenuation parameter in fibrosis prediction in nonalcoholic steatohepatitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jung Il Lee, Hyun Woong Lee and Kwan Sik Lee |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The National Research Foundation of Korea |
NRF-2016R1A2B4015192 |
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| Corresponding author |
Jung Il Lee, MD, PhD, Associate Professor, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul 06273, South Korea. mdflorence@yuhs.ac |
| Keywords |
Fibroscan; Controlled attenuation parameter; Liver stiffness; Nonalcoholic steatohepatitis; Liver fibrosis; |
| Core Tip |
Liver stiffness measurement (LSM) is said to be exaggerated in nonalcoholic fatty liver disease (NAFLD). We investigated the role of controlled attenuation parameter (CAP), a means of measuring steatosis noninvasively, in predicting liver fibrosis by LSM in 184 biopsy proven nonalcoholic steatohepatitis patients. The optimum LSM cutoff for Kleiner fibrosis stage (F) ≥ 2 reflecting CAP values showed higher cutoff with increased CAP tertile (LSM, 8.05 kPa for lower CAP tertile, 9.35 kPa for middle, 10.45 kPa for high CAP tertile). Therefore, we suggest that interpretation of LSM in patients with NAFLD should take CAP scores into account in order to avoid unnecessary liver biopsy. |
| Citation |
Lee JI, Lee HW, Lee KS. Value of controlled attenuation parameter in fibrosis prediction in nonalcoholic steatohepatitis. World J Gastroenterol 2019;25(33): 4959-4969 |
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Received |
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2019-04-24 01:03 |
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Peer-Review Started |
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2019-04-24 03:57 |
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To Make the First Decision |
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2019-07-22 03:45 |
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Return for Revision |
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2019-07-23 03:08 |
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Revised |
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2019-07-29 09:51 |
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Second Decision |
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2019-08-02 10:13 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-08-07 09:37 |
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Articles in Press |
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2019-08-07 09:37 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-04 03:26 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Assistant Editor |
Xiang Li |
| Science Editor |
Jia-Ping Yan |
| Reviewer Code |
03647461, 03576082, and 02539179 |
| Editorial Director |
Ze-Mao Gong |
| Journal Chief Editor |
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| Company Chief Editor |
Lian-Sheng Ma |
| Language Editor |
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| Electronic Editor |
Yu-Jie Ma |
| Responsible Electronic Editor |
Yu-Jie Ma |
| Responsible Science Editor |
Ze-Mao Gong |
| Proofing Editorial Director |
Jin-Lei Wang |
| Proofing Editor-in-Chief |
Lian-Sheng Ma |
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