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Articles in Press
8/21/2019 6:54:48 PM | Browse: 339 | Download: 278
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Minireviews |
Article Title |
Immune checkpoint inhibitor-induced diarrhea/colitis: Endoscopic and pathologic findings
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Manuscript Source |
Invited Manuscript |
All Author List |
Tsutomu Nishida, Hideki Iijima and Shiro Adachi |
Funding Agency and Grant Number |
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Corresponding Author |
Tsutomu Nishida, MD, PhD, Doctor, Department of Gastroenterology, Toyonaka Municipal Hospital, 4-14-1 Shibahara, Toyonaka, Osaka 560-8565, Japan. tnishida.gastro@gmail.com |
Key Words |
Immune checkpoint inhibitor; Colitis; Diarrhea; Endoscopic; Pathologic; |
Core Tip |
Immune checkpoint inhibitor (ICPI)-induced colitis/diarrhea is frequent and recognized not only by oncologists but also by gastroenterologists or endoscopists. The endoscopic findings resemble those of inflammatory bowel disease to a certain extent, particularly ulcerative colitis, but are not identical. The pathological findings of ICPI-induced colitis may vary among drug classes. The findings show acute or chronic phases but may depend on the diagnostic timing or treatment intervention. Colonoscopy with biopsy is necessary to confirm ICPI-induced colitis, and early evaluation may avoid exacerbating or prolonging colitis due to treatment resistance. |
Citation |
Nishida T, Iijima H, Adachi S. Immune checkpoint inhibitor-induced diarrhea/colitis: Endoscopic and pathologic findings. World J Gastrointest Pathophysiol 2019; 10(2): 17-28 |
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Received |
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2019-04-28 01:54 |
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Peer-Review Started |
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2019-05-09 02:21 |
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To Make the First Decision |
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2019-06-13 02:13 |
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Return for Revision |
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2019-06-17 03:32 |
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Revised |
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2019-06-30 23:56 |
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Second Decision |
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2019-08-21 03:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-08-21 18:54 |
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Articles in Press |
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2019-08-21 18:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-05 03:54 |
ISSN |
2150-5330 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
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