Publication Name	World Journal of Gastroenterology
Manuscript ID	48833
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Additional laparoscopic gastrectomy after noncurative endoscopic submucosal dissection for early gastric cancer: A single-center experience
Manuscript Source	Unsolicited Manuscript
All Author List	Yan-Tao Tian, Fu-Hai Ma, Gui-Qi Wang, Yue-Ming Zhang, Dou-Li Zhou, Yi-Bin Xie, Yu-Xin Zhong, Ying-Tai Chen, Quan Xu and Dong-Bing Zhao
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81772642 Beijing Municipal Science and Technology Commission Z161100000116045 Capital’s Funds for Health Improvement and Research CFH 2018-2-4022
Corresponding Author	Dong-Bing Zhao, MD, Doctor, Professor, Surgeon, Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. dbzhao2003@sina.com
Key Words	Early gastric cancer; Endoscopic submucosal dissection; Laparoscopic gastrectomy; Residual cancer; Lymph node metastasis;
Core Tip	It is controversial whether additional gastrectomy is necessary for all patients that do not meet the curative criteria after endoscopic submucosal dissection (ESD). Therefore, it would be valuable to determine which factors could increase the risks of residual cancer or lymph node metastasis in patients after noncurative ESD of in order to avoid unnecessary surgery. We found the gastrectomy was necessary not only for patients who had positive margin in ESD, but also for cases with neural invasion, undifferentiated type and submucosal invasion more than 500 µm. Laparoscopic gastrectomy is a safe, minimally invasive, and feasible procedure for additional surgery after noncurative ESD.
Citation	Tian YT, Ma FH, Wang GQ, Zhang YM, Dou LZ, Xie YB, Zhong YX, Chen YT, Xu Q, Zhao DB. Additional laparoscopic gastrectomy after noncurative endoscopic submucosal dissection for early gastric cancer: A single-center experience. World J Gastroenterol 2019; 25(29): 3996-4006

Received	2019-05-05 02:08
Peer-Review Started	2019-05-06 07:49
To Make the First Decision	2019-06-10 08:21
Return for Revision	2019-06-14 01:42
Revised	2019-06-28 14:13
Second Decision	2019-07-05 10:34
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-07-05 23:37
Articles in Press	2019-07-05 23:37
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-07-17 01:45
Typeset the Manuscript	2019-08-06 02:33

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com