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Publication Name World Journal of Gastroenterology
Manuscript ID 49130
Country of Manuscript Source Slovenia
Specialty Gastroenterology and Hepatology
Manuscript Type Minireviews
Article Title Helicobacter pylori virulence genes
Manuscript Source Invited Manuscript
All Author List Anja Šterbenc, Erika Jarc, Mario Poljak and Matjaž Homan
Funding Agency and Grant Number
Corresponding author Matjaž Homan, MD, PhD, Assistant Professor, Department of Gastroenterology, Hepatology and Nutrition, University Children’s Hospital, Faculty of Medicine, University of Ljubljana, Bohoričeva 20, Ljubljana 1000, Slovenia. matjaz.homan@guest.arnes.si
Keywords Helicobacter pylori; Virulence genes; Disease association; Children; Adults; Outer membrane proteins
Core Tip The assessment of pathogenicity of a plethora of Helicobacter pylori (H. pylori) virulence genes appears to be relatively difficult. In specific, H. pylori isolates show a high degree of geographic variability, with certain H. pylori genotypes being associated with a more severe clinical outcome in some regions, while presenting as virtually harmless variants in other studied populations. To date, cagA and certain allelic variants of vacA have been most consistently associated with severe gastroduodenal disease in both children and adults, whereas the role of outer membrane proteins, such as babA2, sabA, homB and oipA, is somewhat more ambiguous.
Citation Šterbenc A, Jarc E, Poljak M, Homan M. Helicobacter pylori virulence genes. World J Gastroenterol 2019; 25(33): 4870-4884
Received
2019-05-18 05:31
Peer-Review Started
2019-05-20 07:55
To Make the First Decision
2019-07-22 03:33
Return for Revision
2019-07-23 02:09
Revised
2019-07-29 09:02
Second Decision
2019-08-02 10:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-08-07 09:35
Articles in Press
2019-08-07 09:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-09-04 03:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Xiang Li
Science Editor Jia-Ping Yan
Reviewer Code 02682861, 00717554, and 00183445
Editorial Director Ze-Mao Gong
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Electronic Editor Yu-Jie Ma
Responsible Electronic Editor Yu-Jie Ma
Responsible Science Editor Ze-Mao Gong
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Full Article (PDF) WJG-25-4870.pdf
Full Article (Word) WJG-25-4870.docx
Manuscript File 49130-Review.docx
Answering Reviewers 49130-Answering reviewers.pdf
Audio Core Tip 49130-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 49130-Conflict-of-interest statement.pdf
Copyright License Agreement 49130-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 49130-Language certificate.pdf
Peer-review Report 49130-Peer-review(s).pdf
Scientific Misconduct Check 49130-Scientific misconduct check.pdf
Scientific Editor Work List 49130-Scientific editor work list.pdf