Publication Name	World Journal of Gastroenterology
Manuscript ID	49426
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Case Control Study
Article Title	Liver stiffness and serum markers for excluding high-risk varices in patients who do not meet Baveno VI criteria
Manuscript Source	Unsolicited Manuscript
All Author List	Hong Zhou, Jun Long, Han Hu, Cai-Yun Tian and Shi-De Lin
Funding Agency and Grant Number	Funding Agency Grant Number the Funds of Chinese National Natural Science Foundation Project 81860114
Corresponding Author	Shi-De Lin, MD, Occupational Physician, Professor, Department of Infectious Diseases, Affiliated Hospital of Zunyi Medical University, 201 Dalian street, Zunyi 563003, Guizhou Province, China. linshide6@zmu.edu.cn
Key Words	Baveno VI; Esophageal varices; Liver cirrhosis; Liver stiffness measurement; Serum markers of liver fibrosis;
Core Tip	In patients with hepatitis B virus (HBV)-related compensated cirrhosis who did not meet the Baveno VI criteria, the prevalence of high-risk varices among patients with alanine transaminase (ALT) or total bilirubin (TBil) ≥ 2 upper limit of normal (ULN) was significantly lower compared to patients with ALT and TBil < 2 ULN. In the 41 patients with ALT and TBil < 2 ULN, liver stiffness measurement (LSM) < 20.6 kPa spared 39.0% of gastroscopies without missing high-risk varices (HRVs). In the 91 patients with ALT or TBiL ≥ 2 ULN, Lok index ≤ 0.5596 or platelet (PLT) > 100×109/L further spared 39.6% and 43.9% of gastroscopies, respectively, without missing HRVs.
Citation	Zhou H, Long J, Hu H, Tian CY, Lin SD. Liver stiffness and serum markers for excluding high-risk varices in patients who do not meet Baveno VI criteria. World J Gastroenterol 2019; 25(35): 5323-5333

Received	2019-05-29 10:29
Peer-Review Started	2019-05-30 06:11
To Make the First Decision	2019-07-22 03:42
Return for Revision	2019-07-23 06:19
Revised	2019-07-30 06:30
Second Decision	2019-08-23 10:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-08-24 04:49
Articles in Press	2019-08-24 04:49
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-09-01 08:18
Typeset the Manuscript	2019-09-17 01:24

ISSN	1007-9327 (print) and 2219-2840 (online)
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