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10/17/2019 6:29:47 AM | Browse: 494 | Download: 446
Publication Name World Journal of Gastroenterology
Manuscript ID 49772
Country/Territory Germany
Category Surgery
Manuscript Type Retrospective Study
Article Title Bacterobilia in pancreatic surgery-conclusions for perioperative antibiotic prophylaxis
Manuscript Source Unsolicited Manuscript
All Author List Colin Markus Krueger, Ulrich Adam, Thomas Adam, Axel Kramer, Claus D Heidecke, Frank Makowiec and Hartwig Riediger
Funding Agency and Grant Number
Corresponding Author Colin Markus Krueger, FACS, MD, PhD, Chief Physician, Postdoc, Surgeon, Department of Surgery, Immanuel Hospital Ruedersdorf, Seebad 82/83, Ruedersdorf b. BErlin 15562, Brandenburg, Germany. cm.krueger@immanuel.de
Key Words Pancreatic surgery; Bacteriobilia; Antibiotic prophylaxis; Cholestasis; Cholangiopancreatography; Endoscopic retrograde
Core Tip The aim of our retrospective study was to analyze the microbial profile of bacteriobilia in patients undergoing pancreatic head resection (n = 285). Patients with preoperative biliary drainage (PBD +) had a significantly elevated risk of bacteriobilia. In those cases, the contamination was polymicrobiotic. Enterococcus was significantly more frequent in PBD +. Our standard preoperative antibiotic prophylaxis reaches an overall sensitivity rate of 60% and a resistance rate of 25% in 342 bacteria. The antibiotic efficiency of Imipenem and Piperacillin/Tazobactam is significantly higher in PBD +. The data on polymicrobial colonization of the biliary tract may be useful for the decision on antibiotic treatment in case of postoperative infection until the final results from the intraoperative smear are available. A more potent alternative for prophylactic application, however, was not found among the examined antibiotics.
Citation Krüger CM, Adam U, Adam T, Kramer A, Heidecke CD, Makowiec F, Riediger H. Bacterobilia in pancreatic surgery-conclusions for perioperative antibiotic prophylaxis. World J Gastroenterol 2019; 25(41): 6238-6247
Received
2019-07-12 01:51
Peer-Review Started
2019-07-12 06:36
To Make the First Decision
2019-08-19 00:56
Return for Revision
2019-08-20 07:57
Revised
2019-10-10 18:35
Second Decision
2019-10-16 12:21
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-10-17 06:29
Articles in Press
2019-10-17 06:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-10-28 02:46
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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