Publication Name	World Journal of Gastroenterology
Manuscript ID	49835
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Study on serum amyloid A levels in patients with liver diseases
Manuscript Source	Unsolicited Manuscript
All Author List	Zi-Ying Yuan, Xing-Xin Zhang, Yu-Jing Wu, Zhi-Ping Zeng, Wei-Min She, Shi-Yao Chen, Yuan-Qing Zhang and Jin-Sheng Guo
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 91129705 National Natural Science Foundation of China 81070340 National Natural Science Foundation of China 30570825 Shanghai Pujiang Talent Program 09PJ1402600
Corresponding Author	Jin-Sheng Guo, FAASLD, MD, Chief Physician, Professor, Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Shanghai 200032, China. guo.jinsheng@zs-hospital.sh.cn
Key Words	Serum amyloid A; Liver diseases; Pyogenic liver abscess; Chronic hepatitis B; Inflammation;
Core Tip	Serum amyloid A (SAA) is an acute phase protein known to have diagnostic and prognostic value in many diseases. However, the SAA levels and its clinical significance in various liver diseases haven’t been reported. Our study found that serum level of SAA is a sensitive biomarker for inflammatory activity of pyogenic liver abscess, and to a less extent, to reflect mild inflammatory status of autoimmune liver diseases, drug-induced liver injury, chronic active hepatitis B and nonalcoholic steatohepatitis. Serum level of SAA can be confounded by various of inflammatory diseases, thus it is not a specific indicator for certain diseases.
Citation	Yuan ZY, Zhang XX, Wu YJ, Zeng ZP, She WM, Chen SY, Zhang YQ, Guo JS. Study on serum amyloid A levels in patients with liver diseases. World J Gastroenterol 2019; 25(43): 6440-6450

Received	2019-06-24 01:02
Peer-Review Started	2019-06-26 01:03
To Make the First Decision	2019-08-28 01:07
Return for Revision	2019-09-02 08:23
Revised	2019-09-23 14:36
Second Decision	2019-11-06 09:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-11-07 07:51
Articles in Press	2019-11-07 07:51
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-11-10 12:37
Typeset the Manuscript	2019-11-20 08:10

ISSN	1007-9327 (print) and 2219-2840 (online)
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