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Publication Name World Journal of Gastroenterology
Manuscript ID 49853
Country/Territory Thailand
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Autoimmune hepatitis in human immunodeficiency virus-infected patients: A case series and review of the literature
Manuscript Source Invited Manuscript
All Author List Roongruedee Chaiteerakij, Anapat Sanpawat, Anchalee Avihingsanon and Sombat Treeprasertsuk
Funding Agency and Grant Number
Funding Agency Grant Number
the Grant for International Research Integration: Chula Research Scholar; Ratchadaphiseksomphot Endowment Fund, Chulalongkorn University
Center of Excellence for Innovation and Endoscopy in Gastrointestinal Oncology, Faculty of Medicine, Chulalongkorn University
Corresponding Author Sombat Treeprasertsuk, MD, PhD, Professor, Division of Gastroenterology, Department of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, 1873 Rama IV Road, Patumwan, Bangkok 10330, Thailand. battan5410@gmail.com
Key Words Autoimmune hepatitis; Human immunodeficiency virus; Liver biopsy; Immunosuppression; Autoimmunity; Antiretroviral therapy; Case report
Core Tip Elevated liver enzymes are a common problem in human immunodeficiency virus (HIV)-infected patients. Clinical manifestations of autoimmune hepatitis (AIH) range from no symptoms to mild chronic hepatitis to acute severe hepatitis leading to fulminant hepatic failure or cirrhosis. The diagnosis of AIH requires thorough investigation. It is crucial to perform liver biopsy to confirm the diagnosis. Although rare, AIH should be considered a differential diagnosis in HIV-infected patients presenting with elevated aminotransferase enzyme levels after the exclusion of other common causes of hepatitis. It is believed that this condition occurs due to immune reconstitution inflammatory syndrome (IRIS). Immunosuppressive drugs are the mainstay of treatment and can be used safely in HIV-infected patients.
Citation Chaiteerakij R, Sanpawat A, Avihingsanon A, Treeprasertsuk S. Autoimmune hepatitis in human immunodeficiency virus-infected patients: A case series and review of the literature. World J Gastroenterol 2019; 25(35): 5388-5402
Received
2019-06-22 07:38
Peer-Review Started
2019-06-25 10:30
To Make the First Decision
2019-07-22 04:24
Return for Revision
2019-07-24 09:20
Revised
2019-08-14 01:22
Second Decision
2019-08-23 10:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-08-24 04:44
Articles in Press
2019-08-24 04:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-09-17 01:23
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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