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9/10/2019 9:00:36 PM | Browse: 46 | Download: 15
Publication Name World Journal of Gastroenterology
Manuscript ID 50513
Country of Manuscript Source China
Specialty Gastroenterology and Hepatology
Manuscript type Case Control Study
Article Title Correlation of plasma miR-21 and miR-93 with radiotherapy and chemotherapy efficacy and prognosis in patients with esophageal squamous cell carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Wen-Tao Wang, Chang-Qing Guo, Guang-Hui Cui and Song Zhao
Funding Agency and Grant Number
Correspondence To Song Zhao, MD, Doctor, Department of Thoracic Surgery, First Affiliated Hospital of Zhengzhou University, 12th floor, Building 6, Zhengzhou University first affiliated Hospital, No. 1 Longhu Middle Ring Road, Jinshui District, Zhengzhou City, Henan Province, Zhengzhou 450000, China. zhaosong1212@qq.com
Keywords miR-21; miR-93; Esophageal squamous cell carcinoma; Radiotherapy and chemotherapy; Prognosis; Diagnosis
Core Tip In order to observe the roles of miR-21 and miR-93 in radiotherapy and chemotherapy efficacy and prognosis on esophageal squamous cell carcinoma (ESCC), real time Quantitative polymerase chain reaction was adopted to determine the expressions of plasma miR-21 and miR-93 in ESCC patients. Multivariate Logistic regression analysis revealed that patients with high T stage and M stage and high expressions of miR-21(> 5.80) and miR-93 (> 4.71) suffered increased risks of ineffective radiotherapy and chemotherapy, and multivariate Cox regression analysis revealed that patients with high T stage, N stage, and M stage, and high expressions of miR-21 (> 5.60), and miR-93 (> 3.87) suffered increased risk of death in 3 years.
Citation Wang WT, Guo CQ, Cui GH, Zhao S. Correlation of plasma miR-21 and miR-93 with radiotherapy and chemotherapy efficacy and prognosis in patients with esophageal squamous cell carcinoma. World J Gastroenterol 2019; In press
Received
2019-07-24 08:52
Peer-Review Started
2019-07-24 08:52
To Make the First Decision
2019-08-19 00:46
Return for Revision
2019-08-23 01:14
Revised
2019-09-08 14:06
Second Decision
2019-09-10 10:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-09-10 21:00
Articles in Press
2019-09-10 21:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-09-16 23:30
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Ruo-Yu Ma
Reviewer Code 03806663, and 01551804
Editorial Director Ze-Mao Gong
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor Tian-Qi Wang
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 50513-Review_Edited.doc
Answering Reviewers 50513-Answering reviewers.pdf
Audio Core Tip 50513-Audio core tip.mp3
Biostatistics Review Certificate 50513-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 50513-Conflict-of-interest statement.pdf
Copyright License Agreement 50513-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 50513-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 50513-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 50513-Language certificate.pdf
Peer-review Report 50513-Peer-review(s).pdf
Scientific Misconduct Check 50513-Bing-Tang JZ-2.png
Scientific Misconduct Check 50513-Scientific misconduct check.pdf
Scientific Editor Work List 50513-Scientific editor work list.pdf