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Publication Name World Journal of Diabetes
Manuscript ID 50603
Country of Manuscript Source Nigeria
Specialty Physiology
Manuscript Type Basic Study
Article Title Vitamin C ameliorated cardiac autonomic neuropathy in type 2 diabetic rats
Manuscript Source Unsolicited Manuscript
All Author List Temitope Deborah Fabiyi-Edebor
Funding Agency and Grant Number
Corresponding author Temitope Deborah Fabiyi-Edebor, PhD, Senior Lecturer, Lecturing, Department of Physiology, Afe Babalola University, Kilometres 8.5 Afe Babalola Way, Ado 5454, Ekiti, Nigeria. debbyteefab@gmail.com
Keywords Vitamin C; Oxidative stress; Heart rate variability; Tyrosine Hydroxylase; Autonomic nerve; Neuropathy
Core Tip This study reveals that Vitamin C maintained normal heart rate variability, blood pressure and sympathetic tone in type 2 diabetic rats. Thus, preventing the symptoms of cardiac autonomic neuropathy. This is done via mechanisms related to downregulation of oxidative stress, inflammation and dyslipidaemia. Vitamin C may therefore possess cardio-autonomic nerve protection potential and may be used to prevent the development of cardiac autonomic neuropathy in type 2 diabetic subjects.
Citation Fabiyi-Edebor TD. Vitamin C ameliorated cardiac autonomic neuropathy in type 2 diabetic rats. World J Diabetes 2020; In press
Received
2019-08-06 21:09
Peer-Review Started
2019-08-06 21:10
To Make the First Decision
2019-09-23 00:59
Return for Revision
2019-09-25 07:35
Revised
2019-12-07 07:46
Second Decision
2020-01-13 10:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-01-13 21:51
Articles in Press
2020-01-13 21:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jia-Ping Yan
Reviewer Code 02446387, and 00505246
Editorial Director Ruo-Yu Ma
Journal Chief Editor
Company Chief Editor Na Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 50603-Review.docx
Answering Reviewers 50603-Answering reviewers.pdf
Audio Core Tip 50603-Audio core tip.mp3
Biostatistics Review Certificate 50603-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 50603-Conflict-of-interest statement.pdf
Copyright License Agreement 50603-Copyright license agreement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 50603-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 50603-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 50603-Language certificate.pdf
Peer-review Report 50603-Peer-review(s).pdf
Scientific Misconduct Check 50603-Scientific misconduct check.pdf
Scientific Editor Work List 50603-Scientific editor work list.pdf