Publication Name	World Journal of Transplantation
Manuscript ID	51185
Country	Italy

Category	Transplantation
Manuscript Type	Review
Article Title	Therapeutic apheresis in kidney transplantation: An updated review
Manuscript Source	Invited Manuscript
All Author List	Maurizio Salvadori and Aris Tsalouchos
Funding Agency and Grant Number
Corresponding Author	Maurizio Salvadori, MD, Professor, Department of Transplantation Renal Unit, Careggi University Hospital, Viale Pieraccini 18, Florence 50139, Italy. maurizio.salvadori1@gmail.com
Key Words	Kidney transplantation; Therapeutic plasma exchange; Double-filtration plasmapheresis; Immunoadsorption; Extracorporeal photopheresis; Desensitization
Core Tip	Kidney transplantation is the treatment of choice for patients with end-stage renal disease. However, pre-transplant immunological barriers and post-transplant clinical conditions still influence negatively graft and patient’s survival. Therapeutic aphaeresis can be applied in many of these conditions using a variety of devices and procedural approaches. This topic review will present a critical evaluation of the available modalities and examine the evidence supporting the application of therapeutic aphaeresis in kidney transplantation as an adjunctive therapeutic option in protocols both for pre-operative procedures and during the post-transplant period.
Citation	Salvadori M, Tsalouchos A. Therapeutic apheresis in kidney transplantation: An updated review. World J Transplant 2019; 9(6):103-122

Received	2019-09-01 15:05
Peer-Review Started	2019-09-01 15:05
To Make the First Decision	2019-09-23 03:08
Return for Revision	2019-09-23 03:42
Revised	2019-10-02 11:14
Second Decision	2019-10-12 06:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-10-15 21:33
Articles in Press	2019-10-15 21:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-10-25 12:25

ISSN	2220-3230 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com