Publication Name	World Journal of Gastroenterology
Manuscript ID	51459
Country	China

Category	Engineering, Biomedical
Manuscript Type	Retrospective Study
Article Title	Radiomics model based on preoperative gadoxetic acid-enhanced MRI for predicting liver failure
Manuscript Source	Unsolicited Manuscript
All Author List	Wang-Shu Zhu, Si-Ya Shi, Ze-Hong Yang, Chao Song and Jun Shen
Funding Agency and Grant Number	Funding Agency Grant Number the Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme (2017) the Guangdong Natural Science Foundation 2017A030313777
Corresponding Author	Jun Shen, MD, Professor, Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong Province, China. shenjun@mail.sysu.edu.cn
Key Words	Liver failure; Radiomics; Gadoxetic acid; Magnetic resonance imaging; Hepatocellular carcinoma;
Core Tip	Serological indexes, indocyanine green clearance rate at 15 min, liver volumetry, and clinical scoring systems are commonly used to determine liver function capacity and predict postoperative residual liver function. However, these indexes are not sufficiently accurate for predicting the risk of postoperative liver failure. We constructed a radiomics signature based on preoperative hepatobiliary phase gadoxetic acid-enhanced magnetic resonance imaging. This radiomics signature achieves favorable performance in predicting liver failure in cirrhotic patients with hepatocellular carcinoma after major hepatectomy. Incorporating indocyanine green clearance rate at 15 min into the radiomics signature further improves the predictive performance for postoperative liver failure.
Citation	Zhu WS, Shi SY, Yang ZH, Song C, Shen J. Radiomics model based on preoperative gadoxetic acid-enhanced MRI for predicting liver failure. World J Gastroenterol 2020; 26(11): 1208-1220

Received	2019-10-13 14:57
Peer-Review Started	2019-10-12 04:38
To Make the First Decision
Return for Revision	2020-01-13 18:36
Revised	2020-02-18 15:57
Second Decision	2020-02-20 10:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-02-21 06:07
Articles in Press	2020-02-21 06:07
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-03-04 22:22
Typeset the Manuscript	2020-03-18 01:47

ISSN	1007-9327 (print) and 2219-2840 (online)
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