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Publication Name World Journal of Gastroenterology
Manuscript ID 51535
Country of Manuscript Source United States
Specialty Gastroenterology and Hepatology
Manuscript Type Review
Article Title Therapies to modulate gut microbiota: Past, present and future
Manuscript Source Invited Manuscript
All Author List Akshita Gupta, Srishti Saha and Sahil Khanna
Funding Agency and Grant Number
Corresponding author Sahil Khanna, MBBS, MSc, Assistant Professor, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First St SW, Rochester, MN55905, United States. khanna.sahil@mayo.edu
Keywords Fecal microbiota transplantation; Microbial replacement therapies; Clostridioides difficile infection; Microbiome; Microbiota; Inflammatory bowel disease
Core Tip The human gut microbiota comprises of a diverse array of microorganisms responsible for the maintenance of health. Disruption of this microbial milieu has been implicated in various disorders. These include, but are not limited to, diseases such as Clostridioides difficile infection and inflammatory bowel disease. Microbial replacement therapy or fecal microbiota transplantation is highly effective for treating recurrent Clostridioides difficile infection. Its role in other gastrointestinal and non-gastrointestinal disorders is under investigation. This review summarizes the current indications and evidence for the use of such therapies, and briefly touches upon potential therapeutic applications in the future.
Citation Gupta A, Saha S, Khanna S. Therapies to modulate gut microbiota: Past, present and future. World J Gastroenterol 2020; In press
Received
2019-09-20 17:36
Peer-Review Started
2019-09-20 17:36
To Make the First Decision
2019-12-19 00:18
Return for Revision
2019-12-19 02:49
Revised
2020-02-03 16:41
Second Decision
2020-02-14 10:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-02-14 22:37
Articles in Press
2020-02-14 22:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jin-Lei Wang
Reviewer Code 02462498, 01434943, 03646675, and 03699937
Editorial Director Ze-Mao Gong
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 51535-Review.docx
Answering Reviewers 51535-Answering reviewers.pdf
Audio Core Tip 51535-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 51535-Conflict-of-interest statement.pdf
Copyright License Agreement 51535-Copyright license agreement.pdf
Peer-review Report 51535-Peer-review(s).pdf
Scientific Misconduct Check 51535-Scientific misconduct check.pdf
Scientific Editor Work List 51535-Scientific editor work list.pdf