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Publication Name World Journal of Gastroenterology
Manuscript ID 51551
Country/Territory China
Category Gastroenterology and Hepatology
Manuscript Type Case Report
Article Title Flushing as atypical initial presentation of functional gallbladder neuroendocrine carcinoma: A case report
Manuscript Source Unsolicited Manuscript
All Author List Ming Jin, Bo Zhou, Xiong-Ling Jiang, Qi-Yi Zhang, Xiang Zheng, Yuan-Cong Jiang and Sheng Yan
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81572975
Key Research and Development Project of Science and Technology Department of Zhejiang, China 2015C03053
Corresponding author Sheng Yan, MD, PhD, Chief Doctor, Department of General Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou 310009, China. shengyan@zju.edu.cn
Keywords Malignant carcinoid syndrome; Neuroendocrine tumors; Carcinoma; Gallbladder; Carcinoid tumor; Case report
Core Tip Neuroendocrine neoplasms are rarely located in gallbladder, and carcinoid syndrome is exceedingly rare in patients with gallbladder (GB)- neuroendocrine neoplasms. We present herein, a rare case of GB neuroendocrine carcinoma in a 65-year-old man, who presented with flushing for 2 mo. En bloc cholecystectomy, resection of hepatic segments IVb and V, pancreaticoduodenectomy and regional lymphadenectomy were performed. Surgery helped to alleviate his symptoms. Distinctive manifestation combined with imaging does help make correct preoperative diagnosis. Radical surgery followed by adjuvant chemotherapy might improve prognosis of advanced GB-neuroendocrine carcinomas.
Citation Jin M, Zhou B, Jiang XL, Zhang QY, Zheng X, Jiang YC, Yan S. Flushing as atypical initial presentation of functional gallbladder neuroendocrine carcinoma: A case report. World J Gastroenterol 2020; 26(6): 686-695
Received
2019-09-27 04:27
Peer-Review Started
2019-09-21 13:33
To Make the First Decision
2019-11-04 08:09
Return for Revision
2019-11-07 10:58
Revised
2019-12-31 09:23
Second Decision
2020-01-08 09:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-01-11 14:18
Articles in Press
2020-01-11 14:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-01-18 23:56
Typeset the Manuscript
2020-02-13 00:23
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jie Wang (Quit in 2020)
Reviewer Code 03261379, 03548113, and 03388124
Editorial Director Ze-Mao Gong
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor Donna Fox
Electronic Editor Yan-Liang Zhang
Responsible Electronic Editor Yan-Liang Zhang
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Full Article (PDF) WJG-26-686.pdf
Full Article (Word) WJG-26-686.docx
Manuscript File 51551-Review-Filipodia(1).docx
Answering Reviewers 51551-Answering reviewers.pdf
Audio Core Tip 51551-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 51551-Conflict-of-interest_statement.pdf
Copyright License Agreement 51551-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 51551-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 51551-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 51551-Language certificate.pdf
Peer-review Report 51551-Peer-review(s).pdf
Scientific Misconduct Check 51551-Scientific misconduct check.pdf
Scientific Editor Work List 51551-Scientific editor work list.pdf