Publication Name	World Journal of Gastroenterology
Manuscript ID	51631
Country	Japan

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Clinical relevance of fluorodeoxyglucose positron emission tomography/computed tomography and magnifying endoscopy with narrow band imaging in decision-making regarding the treatment strategy for esophageal squamous cell carcinoma
Manuscript Source	Invited Manuscript
All Author List	Kazuhiro Toriyama, Masahiro Tajika, Tsutomu Tanaka, Makoto Ishihara, Yutaka Hirayama, Sachiyo Onishi, Nobumasa Mizuno, Takamichi Kuwahara, Nozomi Okuno, Shimpei Matsumoto, Eiichi Sasaki, Tetsuya Abe, Yasushi Yatabe, Kazuo Hara, Keitaro Matsuo, Tsuneo Tamaki and Yasumasa Niwa
Funding Agency and Grant Number
Corresponding Author	Masahiro Tajika, MD, PhD, Chief Doctor, Doctor, Endoscopy, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi, Nagoya 464-8681, Japan. mtajika@aichi-cc.jp
Key Words	18F-fluorodeoxyglucose positron emission tomography; Magnifying endoscopy; Narrow band imaging; Superficial esophageal cancer; Squamous cell carcinoma; Treatment strategy
Core Tip	The role of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) for determining treatment strategies in patients with superficial esophageal squamous cell carcinoma (ESCC) remains unclear. This study aimed to demonstrate whether the combination of FDG uptake with findings of magnifying endoscopy with narrow band imaging (ME-NBI) was useful for determining the treatment strategy. If the combination of FDG uptake with Type B2 and B3 on ME-NBI was taken as an indicator for radical esophagectomy or definitive chemoradiotherapy, the sensitivity, specificity, and accuracy were 78.3%, 91.5%, and 87.8%, respectively. Combined FDG-PET and ME-NBI was useful for determining the treatment strategies in patients with ESCC.
Citation	Toriyama K, Tajika M, Tanaka T, Ishihara M, Hirayama Y, Onishi S, Mizuno N, Kuwahara T, Okuno N, Matsumoto S, Sasaki E, Abe T, Yatabe Y, Hara K, Matsuo K, Tamaki T, Niwa Y. Clinical relevance of fluorodeoxyglucose positron emission tomography/computed tomography and magnifying endoscopy with narrow band imaging in decision-making regarding the treatment strategy for esophageal squamous cell carcinoma. World J Gastroenterol 2019; 25(46): 6767-6780

Received	2019-10-20 09:15
Peer-Review Started	2019-10-20 09:16
To Make the First Decision
Return for Revision	2019-11-10 04:27
Revised	2019-11-21 00:45
Second Decision	2019-12-06 03:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-12-06 22:19
Articles in Press	2019-12-06 22:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-12-13 06:23

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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