Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	51737
Country	Taiwan

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Outcomes associated with the intention of loco-regional therapy prior to living donor liver transplantation for hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Tsung-Han Wu, Yu-Chao Wang, Chih-Hsien Cheng, Chen-Fang Lee, Ting-Jung Wu, Hong-Shiue Chou, Kun-Ming Chan and Wei-Chen Lee
Funding Agency and Grant Number
Corresponding Author	Kun-Ming Chan, MD, Associate Professor, Chief Doctor, Surgeon, Department of General Surgery and Chang Gung Transplantation Institute, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, 5 Fu-Hsing Street, Gui-Shan District, Taoyun 33305, Taiwan. chankunming@cgmh.org.tw
Key Words	Hepatocellular carcinoma; Loco-regional therapy; Living donor liver transplantation; Outcomes; Tumor necrosis; Liver transplantation
Core Tip	Liver transplantation (LT) has become an ideal treatment for liver cirrhosis associated with hepatocellular carcinoma (HCC) as it simultaneously removes the tumors and cures the underlying liver cirrhosis. Living donor LT (LDLT) offers a flexible timing for transplantation providing timeframe for well preparation of transplantation. The study investigates the outcome in relation to the intention of pre-transplantation loco-regional therapy in LDLT for HCC. Although the study is still unable to establish a definitive therapeutic protocol to achieve a beneficial outcome of HCC after LDLT, achieving profound tumor necrosis by loco-regional therapy could also offer better outcomes for patients undergoing LDLT for HCC.
Citation	Wu TH, Wang YC, Cheng CH, Lee CF, Wu TJ, Chou HS, Chan KM, Lee WC. Outcomes associated with the intention of loco-regional therapy prior to living donor liver transplantation for hepatocellular carcinoma. World J Gastrointest Surg 2020; 12(1): 17-27

Received	2019-10-03 08:45
Peer-Review Started	2019-10-03 08:46
To Make the First Decision	2019-10-25 03:00
Return for Revision	2019-10-31 00:50
Revised	2019-11-06 01:34
Second Decision	2019-11-29 11:34
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-11-30 05:05
Articles in Press	2019-11-30 05:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-12-21 08:20

ISSN	1948-9366 (online)
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