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Publication Name World Journal of Critical Care Medicine
Manuscript ID 51981
Country/Territory India
Category Critical Care Medicine
Manuscript Type Observational Study
Article Title Experience with hemoadsorption (CytoSorb<sup>®</sup>) in the management of septic shock patients
Manuscript Source Unsolicited Manuscript
All Author List Yatin Mehta, Chitra Mehta, Ashish Kumar, Joby V George, Aditi Gupta, Saurabh Nanda, Gaurav Kochhar and Arun Raizada
Funding Agency and Grant Number
Corresponding author Yatin Mehta, FRCA, MD, MNAMS, Doctor, Institute of Critical care and Anesthesia, Medanta The Medicity, Sector 38, Gurgaon 122006, Haryana, India. yatin.mehtacriticalcare@gmail.com
Keywords Hemoadsorption; Sepsis; Cytokines; Clinical conditions; Inflammation and extracorporeal;
Core Tip CytoSorb® is a promising new extracorporeal cytokine hemoadsorption device that can modulate the cytokine storm during sepsis. This retrospective study evaluated clinical outcomes after CytoSorb® therapy of 100 patients admitted to intensive care unit with sepsis. We observed a significant reduction in vasopressors dosage in 40 patients who survived. The survivors also had a reduction in all the biomarker levels (procalcitonin, C-reactive protein, serum lactate and bilirubin) and inflammatory markers (interleukin 6, interleukin 10 and tumour necrosis factor) after CytoSorb® therapy. Notably, 28% of patients who were given CytoSorb® therapy < 48 h after onset of septic shock survived.
Citation Mehta Y, Mehta C, Kumar A, George JV, Gupta A, Nanda S, Kochhar G, Raizada A. Experience with hemoadsorption (CytoSorb®) in the management of septic shock patients. World J Crit Care Med 2020; 9(1): 1-12
Received
2019-10-11 11:38
Peer-Review Started
2019-10-11 11:38
To Make the First Decision
2019-11-04 00:32
Return for Revision
2019-11-05 00:24
Revised
2019-12-23 15:06
Second Decision
2020-01-13 10:41
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-01-13 21:39
Articles in Press
2020-01-13 21:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-01-16 09:05
ISSN 2220-3141(online)
Open Access
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Yu-Qiao Wang (Quit in 2020)
Reviewer Code 00503929, 02488399, 01220621, and 03555433
Editorial Director Jia-Ping Yan
Journal Chief Editor
Company Chief Editor Na Ma
Language Editor
Electronic Editor Lu-Lu Qi (Quit in 2020)
Responsible Electronic Editor Lu-Lu Qi (Quit in 2020)
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Full Article (PDF) WJCCM-9-1.pdf
Full Article (Word) WJCCM-9-1.docx
Manuscript File 51981-Review.doc
Answering Reviewers 50603-Answering reviewers.pdf
Audio Core Tip 50603-Audio core tip.mp3
Biostatistics Review Certificate 50603-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 51981-Conflict-of-interest statement.pdf
Copyright License Agreement 51981-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 51981-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 51981-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 51981-Language certificate.pdf
Supplementary Material 51981-Supplementary material.docx
Peer-review Report 50603-Peer-review(s).pdf
Scientific Misconduct Check 51981-Scientific misconduct check.pdf
Scientific Editor Work List 50603-Scientific editor work list.pdf