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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 52190
Country/Territory Netherlands
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Clinical outcomes of patients with duodenal adenocarcinoma and intestinal-type papilla of Vater adenocarcinoma
Manuscript Source Unsolicited Manuscript
All Author List Laura L Meijer, Marin Strijker, Jacob K de Bakker, Jurgen GJ Toennaer, Barbara M Zonderhuis, Hans J van der Vliet, Hanneke Wilmink, Joanne Verheij, Freek Daams, Olivier R Busch, Nicole CT van Grieken, Marc G Besselink and Geert Kazemier
Funding Agency and Grant Number
Funding Agency Grant Number
The Bennink Foundation 2002262
Cancer Center Amsterdam Foundation
Corresponding Author Geert Kazemier, FEBS, MD, PhD, Professor, Surgeon, Surgical Oncologist, Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC - VU University Amsterdam, De Boelelaan 1117, Amsterdam 1081HV, Netherlands. g.kazemier@amsterdamumc.nl
Key Words Duodenal adenocarcinoma; Papilla of Vater adenocarcinoma; Clinical outcomes; Local treatment; Metastases; Survival
Core Tip This study demonstrates the clinical outcome for duodenal adenocarcinoma and intestinal-type papilla of Vater adenocarcinoma, which are rare tumor types of the gastro-intestinal tract. The overall survival is comparable per disease stage, resulting in a median survival of 39 mo. Most patients (79%) are treated with curative intent by surgical resection of the tumor. For patients with metastatic disease, local treatment of metastases was associated with a better overall survival compared to systemic treatment or supportive care. Future prospective studies are needed to confirm this survival benefit.
Citation Meijer LL, Strijker M, de Bakker JK, Toennaer JGJ, Zonderhuis BM, van der Vliet HJ, Wilmink H, Verheij J, Daams F, Busch OR, van Grieken NCT, Besselink MG, Kazemier G. Clinical outcomes of patients with duodenal adenocarcinoma and intestinal-type papilla of Vater adenocarcinoma. World J Gastrointest Oncol 2020; 12(3): 347-357
Received
2019-10-21 19:22
Peer-Review Started
2019-10-21 19:22
To Make the First Decision
Return for Revision
2019-12-05 23:07
Revised
2020-01-04 13:49
Second Decision
2020-01-20 01:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-01-20 02:53
Articles in Press
2020-01-20 02:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-02-13 06:48
Typeset the Manuscript
2020-03-09 01:31
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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