Category |
Gastroenterology & Hepatology |
Manuscript Type |
Observational Study |
Article Title |
Clinical outcomes of patients with duodenal adenocarcinoma and intestinal-type papilla of Vater adenocarcinoma
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Laura L Meijer, Marin Strijker, Jacob K de Bakker, Jurgen GJ Toennaer, Barbara M Zonderhuis, Hans J van der Vliet, Hanneke Wilmink, Joanne Verheij, Freek Daams, Olivier R Busch, Nicole CT van Grieken, Marc G Besselink and Geert Kazemier |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
The Bennink Foundation |
2002262 |
Cancer Center Amsterdam Foundation |
|
|
Corresponding Author |
Geert Kazemier, FEBS, MD, PhD, Professor, Surgeon, Surgical Oncologist, Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC - VU University Amsterdam, De Boelelaan 1117, Amsterdam 1081HV, Netherlands. g.kazemier@amsterdamumc.nl |
Key Words |
Duodenal adenocarcinoma; Papilla of Vater adenocarcinoma; Clinical outcomes; Local treatment; Metastases; Survival |
Core Tip |
This study demonstrates the clinical outcome for duodenal adenocarcinoma and intestinal-type papilla of Vater adenocarcinoma, which are rare tumor types of the gastro-intestinal tract. The overall survival is comparable per disease stage, resulting in a median survival of 39 mo. Most patients (79%) are treated with curative intent by surgical resection of the tumor. For patients with metastatic disease, local treatment of metastases was associated with a better overall survival compared to systemic treatment or supportive care. Future prospective studies are needed to confirm this survival benefit. |
Citation |
Meijer LL, Strijker M, de Bakker JK, Toennaer JGJ, Zonderhuis BM, van der Vliet HJ, Wilmink H, Verheij J, Daams F, Busch OR, van Grieken NCT, Besselink MG, Kazemier G. Clinical outcomes of patients with duodenal adenocarcinoma and intestinal-type papilla of Vater adenocarcinoma. World J Gastrointest Oncol 2020; 12(3): 347-357 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |