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Publication Name World Journal of Gastroenterology
Manuscript ID 52229
Country of Manuscript Source United States
Specialty Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Magnetic resonance imaging biomarkers for pulsed focused ultrasound treatment of pancreatic ductal adenocarcinoma
Manuscript Source Unsolicited Manuscript
All Author List Ezekiel Maloney, Yak-Nam Wang, Ravneet Vohra, Helena Son, Stella Whang, Tatiana Khokhlova, Joshua Park, Kayla Gravelle, Stephanie Totten, Joo Ha Hwang and Donghoon Lee
Funding Agency and Grant Number
Funding Agency Grant Number
National Institutes of Health, National Cancer Institute R01 CA188654
National Institutes of Health, National Cancer Institute R01 CA154451
Corresponding author Donghoon Lee, PhD, Professor, Department of Radiology, University of Washington, SLU C256, 850 Republican Street, Seattle, WA98195, United States. dhoonlee@uw.edu
Keywords Pancreatic adenocarcinoma; Multiparametric magnetic resonance imaging; Focused ultrasound; ; ;
Core Tip In a genetic model of pancreatic ductal adenocarcinoma, clinically translatable, quantitative magnetic resonance imaging methods of T2, glycosaminoglycan chemical exchange saturation transfer, and apparent diffusion coefficient mapping were effective in non-invasively characterizing the treatment effects of pulsed focused ultrasound treatment. Pulsed focused ultrasound treatment has already been shown to improve survival for patients with pancreatic ductal adenocarcinoma in an early clinical trial, and these complimentary magnetic resonance imaging methods could help to advance this promising therapy in larger clinical trials.
Citation Maloney E, Wang YN, Vohra R, Son H, Whang S, Khokhlova T, Park J, Gravelle K, Totten S, Hwang JH, Lee D. Magnetic resonance imaging biomarkers for pulsed focused ultrasound treatment of pancreatic ductal adenocarcinoma. World J Gastroenterol 2020; In press
Received
2019-11-17 04:59
Peer-Review Started
2019-11-17 05:02
To Make the First Decision
Return for Revision
2019-12-23 16:24
Revised
2020-01-12 05:23
Second Decision
2020-02-14 03:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-02-14 22:32
Articles in Press
2020-02-14 22:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Ya-Juan Ma
Reviewer Code 00183086, and 02542970
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 52229-Review.docx
Answering Reviewers 52229-Answering reviewers.pdf
Audio Core Tip 52229-Audio core tip.mp3
Biostatistics Review Certificate 52229-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 52229-Conflict-of-interest_statement.pdf
Copyright License Agreement 52229-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 52229-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 52229-Institutional animal care and use committee statement.pdf
Peer-review Report 52229-Peer-review(s).pdf
Scientific Misconduct Check 52229-Scientific misconduct check.pdf
Scientific Editor Work List 52229-Scientific editor work list.pdf