Publication Name	World Journal of Gastroenterology
Manuscript ID	52356
Country	South Korea

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Basic Study
Article Title	Liver stiffness and perfusion changes for hepatic sinusoidal obstruction syndrome in rabbit model
Manuscript Source	Unsolicited Manuscript
All Author List	Jaeseung Shin, Haesung Yoon, Yoon Jin Cha, Kyunghwa Han, Mi-Jung Lee, Myung-Joon Kim and Hyun Joo Shin
Funding Agency and Grant Number	Funding Agency Grant Number Faculty Research Grant of Yonsei University College of Medicine for 2017 6-2017-0090
Corresponding Author	Hyun Joo Shin, MD, PhD, Assistant Professor, Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, South Korea. lamer-22@yuhs.ac
Key Words	Hepatic sinusoidal obstruction syndrome; Elasticity imaging techniques; Iodine; Computed tomography; Liver; Animals
Core Tip	Noninvasive imaging methods are required for the early diagnosis and severity assessment of hepatic sinusoidal obstruction syndrome (SOS). This study showed that liver stiffness on supersonic shear wave imaging was significantly elevated as hepatic SOS progressed in rabbit model. In addition, as hepatic SOS progressed, perfusion parameters measured on dual energy computed tomography were significantly elevated. We suggested that quantitative imaging with supersonic shear wave imaging and dual energy computed tomography could aid in the early diagnosis of hepatic SOS.
Citation	Shin J, Yoon H, Cha YJ, Han K, Lee MJ, Kim MJ, Shin HJ. Liver stiffness and perfusion changes for hepatic sinusoidal obstruction syndrome in rabbit model. World J Gastroenterol 2020; 26(7): 706-716

Received	2019-10-29 09:19
Peer-Review Started	2019-10-29 09:19
To Make the First Decision
Return for Revision	2019-12-23 19:03
Revised	2020-01-08 14:29
Second Decision	2020-01-18 08:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-01-18 18:51
Articles in Press	2020-01-18 18:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-02-17 01:23

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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