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Publication Name World Journal of Gastroenterology
Manuscript ID 52382
Country of Manuscript Source China
Specialty Gastroenterology and Hepatology
Manuscript Type Observational Study
Article Title Diverting colostomy is an effective and reversible option for severe hemorrhagic radiation proctopathy
Manuscript Source Unsolicited Manuscript
All Author List Zi-Xu Yuan, Qi-Yuan Qin, Miao-Miao Zhu, Qing-Hua Zhong, Alessandro Fichera, Hui Wang, Huai-Ming Wang, Xiao-Yan Huang, Wu-Teng Cao, Ye-Biao Zhao, Lei Wang and Teng-Hui Ma
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China (NSFC) grant 8157120115, 81803163
Natural Science Foundation of Guangdong PhD Start Grant 2018A030310320 and 2018A030310319
Corresponding author Teng-Hui Ma, MD, PhD, Doctor, Surgeon, Surgical Oncologist, Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-Sen University, 26 Yuancun Erheng Road, Guangzhou 510655, Guangdong Province, China. austin_2004@163.com
Keywords Chronic radiation proctitis; Hemorrhage; Colostomy; Anorectal function; Quality of life;
Core Tip This study evaluated the efficacy of colostomy and stoma reversal in severe hemorrhagic chronic radiation proctopathy. After screening 738 patients, 14 patients in the colostomy group and 25 in the conservative treatment group were included. All 14 colostomy patients achieved complete remission of bleeding, and the colostomy was reversed in 13 patients. The hemoglobin level increased gradually after the stoma. However, no bleeding cessation was observed in the conservative group. Anorectal functions and quality of life were improved after stoma reversal. In conclusion, diverting colostomy is an effective option and can be reversed in severe hemorrhagic chronic radiation proctopathy.
Citation Yuan ZX, Qin QY, Zhu MM, Zhong QH, Fichera A, Wang H, Wang H, Huang XY, Cao WT, Zhao YB, Wang L, Ma TH. Diverting colostomy is an effective and reversible option for severe hemorrhagic radiation proctopathy. World J Gastoenterol 2020; In press
Received
2019-10-30 12:38
Peer-Review Started
2019-10-30 12:40
To Make the First Decision
Return for Revision
2019-11-22 03:08
Revised
2019-12-04 15:24
Second Decision
2020-02-14 12:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-02-14 22:35
Articles in Press
2020-02-14 22:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-02-17 02:42
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jennifer C van Velkinburgh
Reviewer Code 03737603, and 05225448
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor Tian-Qi Wang
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 52382-Review_WangTQ.docx
Answering Reviewers 52382-Answering reviewers.pdf
Audio Core Tip 52382-Audio core tip.m4a
Biostatistics Review Certificate 52382-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 52382-Conflict-of-interest statement.pdf
Copyright License Agreement 52382-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 52382-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 52382-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 52382-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 52382-Language certificate.pdf
Supplementary Material 52382-Supplementary material.docx
Peer-review Report 52382-Peer-review(s).pdf
Scientific Misconduct Check 52382-Scientific misconduct check.pdf
Scientific Editor Work List 52382-Scientific editor work list.pdf