Publication Name	World Journal of Gastroenterology
Manuscript ID	52382
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Diverting colostomy is an effective and reversible option for severe hemorrhagic radiation proctopathy
Manuscript Source	Unsolicited Manuscript
All Author List	Zi-Xu Yuan, Qi-Yuan Qin, Miao-Miao Zhu, Qing-Hua Zhong, Alessandro Fichera, Hui Wang, Huai-Ming Wang, Xiao-Yan Huang, Wu-Teng Cao, Ye-Biao Zhao, Lei Wang and Teng-Hui Ma
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China (NSFC) grant 8157120115, 81803163 Natural Science Foundation of Guangdong PhD Start Grant 2018A030310320 and 2018A030310319
Corresponding Author	Teng-Hui Ma, MD, PhD, Doctor, Surgeon, Surgical Oncologist, Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-Sen University, 26 Yuancun Erheng Road, Guangzhou 510655, Guangdong Province, China. austin_2004@163.com
Key Words	Chronic radiation proctitis; Hemorrhage; Colostomy; Anorectal function; Quality of life;
Core Tip	This study evaluated the efficacy of colostomy and stoma reversal in severe hemorrhagic chronic radiation proctopathy. After screening 738 patients, 14 patients in the colostomy group and 25 in the conservative treatment group were included. All 14 colostomy patients achieved complete remission of bleeding, and the colostomy was reversed in 13 patients. The hemoglobin level increased gradually after the stoma. However, no bleeding cessation was observed in the conservative group. Anorectal functions and quality of life were improved after stoma reversal. In conclusion, diverting colostomy is an effective option and can be reversed in severe hemorrhagic chronic radiation proctopathy.
Citation	Yuan ZX, Qin QY, Zhu MM, Zhong QH, Fichera A, Wang H, Wang H, Huang XY, Cao WT, Zhao YB, Wang L, Ma TH. Diverting colostomy is an effective and reversible option for severe hemorrhagic radiation proctopathy. World J Gastoenterol 2020; 26(8): 850-864

Received	2019-10-30 12:38
Peer-Review Started	2019-10-30 12:40
To Make the First Decision
Return for Revision	2019-11-22 03:08
Revised	2019-12-04 15:24
Second Decision	2020-02-14 12:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-02-14 22:35
Articles in Press	2020-02-14 22:35
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-02-17 02:42
Typeset the Manuscript	2020-02-25 11:33

ISSN	1007-9327 (print) and 2219-2840 (online)
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