Publication Name	World Journal of Gastroenterology
Manuscript ID	52667
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Protective effects of panax notoginseng saponin on dextran sulfate sodium-induced colitis in rats through phosphoinositide-3-kinase protein kinase B signaling pathway inhibition
Manuscript Source	Unsolicited Manuscript
All Author List	Qing-Ge Lu, Li Zeng, Xiao-Hai Li, Yu Liu, Xue-Feng Du, Guo-Min Bai and Xin Yan
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81704059 Scientific Research Project of Hebei Province Traditional Chinese Medicine Administration 2017130
Corresponding Author	Xin Yan, PhD, Professor, College of Traditional Chinese Medicine, North China University of Science and Technology, No. 21 Bohai Avenue, Caofeidian New Town, Tangshan 063210, Hebei Province, China. y18301212703@163.com
Key Words	Panax notoginseng saponin; Phosphoinositide-3-kinase–protein kinase B signal pathway; Dextran sulfate sodium; Colitis; Rat intestine; Protective effect
Core Tip	Panax notoginseng saponin is a drug widely used for cardiovascular diseases and diabetes, with good proven inhibitory effects on inflammation. Our study also found that panax notoginseng saponin exerted good inhibitory effects on inflammation in dextran sulfate sodium-induced colitis.
Citation	Lu QG, Zeng L, Li XH, Liu Y, Du XF, Bai GM, Yan X. Protective effects of panax notoginseng saponin on dextran sulfate sodium-induced colitis in rats through phosphoinositide-3-kinase protein kinase B signaling pathway inhibition. World J Gastroenterol 2020; 26(11): 1156-1171

Received	2019-11-12 04:30
Peer-Review Started	2019-11-12 04:30
To Make the First Decision
Return for Revision	2019-12-23 17:40
Revised	2019-12-27 07:48
Second Decision	2020-02-20 15:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-02-21 06:04
Articles in Press	2020-02-21 06:04
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-03-04 21:27
Typeset the Manuscript	2020-03-20 02:36

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com