Publication Name	World Journal of Clinical Cases
Manuscript ID	52715
Country	China

Category	Medicine, General & Internal
Manuscript Type	Retrospective Study
Article Title	Upper esophageal sphincter abnormalities on high-resolution esophageal manometry with treatment response of type Ⅱ achalasia
Manuscript Source	Unsolicited Manuscript
All Author List	Can-Ze Huang, Zai-Wei Huang, Hua-Min Liang, Zhen-Jiang Wang, Ting-Ting Guo and Yu-Ping Chen
Funding Agency and Grant Number
Corresponding Author	Yu-Ping Chen, Director, Department of Gastroenterology, Zhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), 79 Kangning Road, Zhuhai 519000, Guangdong Province, China. yuping_chenzhh@163.com
Key Words	Upper esophageal sphincter; High-resolution esophageal manometry; Achalasia; Treatment response; ;
Core Tip	In this retrospective study involving 498 consecutive patients who underwent high-resolution esophageal manometry, we found that impaired relaxation alone was the most common upper esophageal sphincter (UES) abnormality. The incidence rate of type Ⅱ achalasia was significantly higher in subjects with abnormal UES compared with normal UES. Subjects with type Ⅱ achalasia and abnormal UES presented a significantly poorer treatment response than those with normal UES.
Citation	Huang CZ, Huang ZW, Liang HM, Wang ZJ, Guo TT, Chen YP. Upper esophageal sphincter abnormalities on high-resolution esophageal manometry with treatment response of type Ⅱ achalasia. World J Clin Cases 2020; 8(4): 723-735

Received	2019-11-22 08:53
Peer-Review Started	2019-11-22 08:53
To Make the First Decision
Return for Revision	2019-12-23 14:28
Revised	2019-12-26 03:48
Second Decision	2020-01-18 10:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-01-18 18:58
Articles in Press	2020-01-18 18:58
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-01-29 07:57
Typeset the Manuscript	2020-02-14 07:54

ISSN	2307-8960 (online)
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