Publication Name	World Journal of Clinical Cases
Manuscript ID	52767
Country	China

Category	Clinical Neurology
Manuscript Type	Case Report
Article Title	Late-onset multiple acyl-CoA dehydrogenase deficiency with cardiac syncope: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Xue-Qi Pan, Xue-Li Chang, Wei Zhang, Hua-Xing Meng, Jing Zhang, Jia-Ying Shi and Jun-Hong Guo
Funding Agency and Grant Number
Corresponding Author	Jun-Hong Guo, PhD, Doctor, Professor, Department of Neurology, Frist Hospital of Shanxi Medical University, No. 85, Jiefangnan Road, Yingze Disrict, Taiyuan 030001, Shanxi Province, China. neuroguo123@126.com
Key Words	Late-onset multiple acyl-CoA dehydrogenase deficiency; ETFDH; Cardiac syncope; Supraventricular tachycardia; Mitochondrion; Carnitine
Core Tip	Multiple acyl-CoA dehydrogenase deficiency (MADD) is an uncommon autosomal recessive disorder of mitochondrial fatty acid beta-oxidation. Syncope is a transient loss of consciousness due to acute global cerebral hypoperfusion. Late-onset MADD with syncope has not been reported previously. Here, we present a case of late-onset MADD with cardiac syncope, which suggested that we should pay attention to the monitoring of cardiac function and the prevention of cardiac syncope when we diagnose and treat late-onset MADD. Carnitine and riboflavin supplement were beneficial for treating the late-onset MADD with cardiac syncope.
Citation	Pan XQ, Chang XL, Zhang W, Meng HX, Zhang J, Shi JY, Guo JH. Late-onset multiple acyl-CoA dehydrogenase deficiency with cardiac syncope: A case report. World J Clin Cases 2020; 8(5): 995-1001

Received	2019-11-26 13:04
Peer-Review Started	2019-11-26 13:05
To Make the First Decision
Return for Revision	2019-12-30 21:31
Revised	2020-01-09 03:16
Second Decision	2020-02-14 13:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-02-14 22:27
Articles in Press	2020-02-14 22:27
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-02-20 00:55
Typeset the Manuscript	2020-03-04 03:00

ISSN	2307-8960 (online)
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