Publication Name	World Journal of Clinical Cases
Manuscript ID	52972
Country	China

Category	Medicine, Research & Experimental
Manuscript Type	Case Report
Article Title	Extrapontine myelinolysis caused by the rapid correction of pituitrin-induced severe hyponatremia: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Liang-Jie Fang, Ming-Wei Xu, Jian-Ying Zhou and Zhi-jie Pan
Funding Agency and Grant Number	Funding Agency Grant Number the Department of Health of Zhejiang province, China 2016RCA013
Corresponding Author	Zhi-jie Pan, MD, Chief Doctor, Professor, Department of Respiratory Medicine, First Affiliated Hospital, School of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. panzj200709@zju.edu.cn
Key Words	Pituitrin; Hyponatremia; Extrapontine myelinolysis; Case report; ;
Core Tip	Osmotic demyelination syndrome (ODS) is a devastating neurologic disorder often associated with a precipitous rise in serum sodium. Here we describe a rare case of extrapontine myelinolysis that developed after the rapid correction of symptomatic hyponatremia induced by pituitrin to treat a patient with massive hemoptysis. Because ODS is mainly an iatrogenic disease, effective prevention is mandatory. Through an analysis of the previous literature, the risk factors, clinical characteristics and outcomes of vasopressin (pituitrin)-associated ODS are discussed in this article.
Citation	Fang LJ, Xu MW, Zhou JY, Pan ZJ, Extrapontine myelinolysis caused by the rapid correction of pituitrin-induced severe hyponatremia: A case report. World J Clin Cases 2020; 8(5): 946-953

Received	2019-11-29 15:30
Peer-Review Started	2019-11-29 15:30
To Make the First Decision
Return for Revision	2019-12-30 21:24
Revised	2020-01-06 16:51
Second Decision	2020-02-11 13:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2020-02-11 19:18
Articles in Press	2020-02-11 19:18
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-02-14 08:11
Typeset the Manuscript	2020-03-05 01:46

ISSN	2307-8960 (online)
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