Publication Name	World Journal of Clinical Cases
Manuscript ID	52972
Country of Manuscript Source	China

Specialty	Medicine, Research and Experimental
Manuscript Type	Case Report
Article Title	Extrapontine myelinolysis caused by the rapid correction of pituitrin-induced severe hyponatremia: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Liang-Jie Fang, Ming-Wei Xu, Jian-Ying Zhou and Zhi-jie Pan
Funding Agency and Grant Number	Funding Agency Grant Number the Department of Health of Zhejiang province, China 2016RCA013
Corresponding author	Zhi-jie Pan, MD, Chief Doctor, Professor, Department of Respiratory Medicine, First Affiliated Hospital, School of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou 310003, Zhejiang, China. panzj200709@zju.edu.cn
Keywords	Pituitrin; Hyponatremia; Extrapontine myelinolysis; Case report; ;
Core Tip	Osmotic demyelination syndrome (ODS) is a devastating neurologic disorder often associated with a precipitous rise in serum sodium. Here we describe a rare case of extrapontine myelinolysis that developed after the rapid correction of symptomatic hyponatremia induced by pituitrin to treat a patient with massive hemoptysis. Because ODS is mainly an iatrogenic disease, effective prevention is mandatory. Through an analysis of the previous literature, the risk factors, clinical characteristics and outcomes of vasopressin (pituitrin)-associated ODS are discussed in this article.
Citation	Fang LJ, Xu MW, Zhou JY, Pan ZJ, Extrapontine myelinolysis caused by the rapid correction of pituitrin-induced severe hyponatremia: A case report. World J Clin Cases 2020; In press

Received	2019-11-29 15:30
Peer-Review Started	2019-11-29 15:30
To Make the First Decision
Return for Revision	2019-12-30 21:24
Revised	2020-01-06 16:51
Second Decision	2020-02-11 13:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-02-11 19:18
Articles in Press	2020-02-11 19:18
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-02-14 08:11
Typeset the Manuscript

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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Assistant Editor	Assistant Editor
Science Editor	Le Zhang
Reviewer Code	03604107
Editorial Director
Journal Chief Editor
Company Chief Editor	Lian-Sheng Ma
Language Editor	Tian-Qi Wang
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director	Jin-Lei Wang
Proofing Editor-in-Chief	Lian-Sheng Ma

Manuscript File	52972-Review_WangTQ.doc
Answering Reviewers	52972-Answering reviewers.pdf
Audio Core Tip	52972-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	52972-Conflict-of-interest statement.pdf
Copyright License Agreement	52972-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	52972-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	52972-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	52972-Language certificate.pdf
Peer-review Report	52972-Peer-review(s).pdf
Scientific Misconduct Check	52972-Scientific misconduct check.pdf
Scientific Editor Work List	52972-Scientific editor work list.pdf