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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 53086
Country/Territory China
Category Gastroenterology and Hepatology
Manuscript Type Observational Study
Article Title Evaluation of the value of multiparameter combined analysis of serum markers in the early diagnosis of gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Zhi-Guo Zhang, Liang Xu, Peng-Jun Zhang and Lei Han
Funding Agency and Grant Number
Funding Agency Grant Number
National Key R&D Program of China 2016YFC0106604
National Natural Science Foundation of China 81502591
Corresponding author Lei Han, MD, Professor, Department of Oncology, Beijing Daxing District People’s Hospital, No. 26 Huangcun West Street, Beijing 102600, China. zlk60283168@163.com
Keywords Gastric cancer; Gastric polyp; Serum; Artificial neural network; Detection
Core Tip In this study, we aimed to improve the diagnostic value of blood markers for gastric cancer. By comparing the binary logistic regression, discriminant analysis, classification tree and artificial neural network analysis, finally, artificial neural networks had better diagnostic value. When compared healthy control and gastric cancer, gastric polyp and gastric cancer, the area under the curve was 0.992 (0.980, 1.000) and 0.969 (0.948, 0.990), respectively. Based on artificial neural network and serum index, a novel diagnostic model for gastric cancer may be provided for clinical practice.
Citation Zhang ZG, Xu L, Zhang PJ, Han L. Evaluation of the value of multiparameter combined analysis of serum markers in the early diagnosis of gastric cancer. World J Gastrointest Oncol 2020; In press
2019-12-21 08:14
Peer-Review Started
2019-12-21 08:14
To Make the First Decision
Return for Revision
2020-01-19 04:41
2020-02-05 00:32
Second Decision
2020-03-19 10:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-03-22 21:30
Articles in Press
2020-03-22 21:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jin-Lei Wang
Reviewer Code 02530872, 02282572, 02440910, and 02446277
Editorial Director
Journal Chief Editor
Company Chief Editor Na Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 53086-Review.docx
Answering Reviewers 53086-Answering reviewers.pdf
Audio Core Tip 53086-Audio core tip.mp3
Biostatistics Review Certificate 53086-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 53086-Conflict-of-interest statement.pdf
Copyright License Agreement 53086-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 53086-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 53086-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 53086-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 53086-Language certificate.pdf
Peer-review Report 53086-Peer-review(s).pdf
Scientific Misconduct Check 53086-Scientific misconduct check.pdf
Scientific Editor Work List 53086-Scientific editor work list.pdf