Publication Name	World Journal of Hepatology
Manuscript ID	53443
Country	Sweden

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Comparison of four non-alcoholic fatty liver disease detection scores in a Caucasian population
Manuscript Source	Unsolicited Manuscript
All Author List	Lars Lind, Lars Johansson, Håkan Ahlström, Jan W Eriksson, Anders Larsson, Ulf Risérus, Joel Kullberg and Jan Oscarsson
Funding Agency and Grant Number
Corresponding Author	Lars Lind, MD, PhD, Professor, Department of Medical Sciences, Uppsala University, Akademiska sjukhuset, Entrance 40, 5th floor, Uppsala 75185, Sweden. lars.lind@medsci.uu.se
Key Words	Comparison; EFFECT studies; Fatty liver; Non-alcoholic fatty liver disease; Non-invasive indices; Screening
Core Tip	Several non-invasive indices based on routinely available biochemical and physical parameters have been developed for the detection of non-alcoholic fatty liver (NAFLD) disease. However, data comparing the efficacy of these indices within a population-based sample are lacking. Here we compared four non-invasive indices, namely, fatty liver index, lipid accumulation product, hepatic steatosis index, and liver fat score, in a population-based (Prospective investigation of obesity, energy and metabolism study) sample and a high-risk (EFFECT studies) sample. Our study demonstrated differences in NAFLD detection between the scores in the two samples. Of the four evaluated scores, fatty liver index was preferable in the population-based sample (NAFLD prevalence, 23%), whereas liver fat score performed best in the high-risk sample (NAFLD prevalence, 73%).
Citation	Lind L, Johansson L, Ahlström H, Eriksson JW, Larsson A, Risérus U, Kullberg J, Oscarsson J. Comparison of four non-alcoholic fatty liver disease detection scores in a Caucasian population. World J Hepatol 2020; 12(4): 149-159

Received	2019-12-20 18:03
Peer-Review Started	2019-12-20 18:05
To Make the First Decision
Return for Revision	2020-01-06 03:15
Revised	2020-03-16 16:06
Second Decision	2020-03-19 12:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-03-22 21:26
Articles in Press	2020-03-22 21:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-04-18 04:10

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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