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Publication Name World Journal of Stem Cells
Manuscript ID 53592
Country Brazil
Category Orthopedics
Manuscript Type Review
Article Title Bone marrow-derived products: A classification proposal – bone marrow aspirate, bone marrow aspirate concentrate or hybrid?
Manuscript Source Unsolicited Manuscript
All Author List Joseph Purita, José Fábio Santos Duarte Lana, Morey Kolber, Bruno Lima Rodrigues, Tomas Mosaner, Gabriel Silva Santos, Carolina Caliari- Oliveira and Stephany Cares Huber
Funding Agency and Grant Number
Corresponding Author José Fábio Santos Duarte Lana, MD, Chief Doctor, Surgeon, Institute of Bone and Cartilage, 1386 Presidente Kennedy Avenue, Indaiatuba 13334-170, SP, Brazil. josefabiolana@gmail.com
Key Words Bone-marrow classification; Bone-marrow aspirate concentrate; Regenerative medicine; Stem cells; Musculoskeletal disorders; Orthobiologics
Core Tip Degenerative musculoskeletal disorders are one of the top causes of pain and disability in the adult population. The use of certain analgesics delivers short term results but do not address the etiological source of pain and disability. The demand for musculoskeletal tissue regeneration has led to an alternative approach referred to as orthobiologics, which is based on cellular and molecular components capable of promoting tissue repair. Bone marrow aspirate and concentrate are well-known orthobiologics used to treat musculoskeletal conditions. Since bone marrow-derived orthobiologics have not yet been classified, to our knowledge, this manuscript proposes the ACH classification system.
Citation Purita J, Lana JFSD, Kolber M, Rodrigues BL, Mosaner T, Santos GS, Caliari-Oliveira C, Huber SC. Bone marrow-derived products: A classification proposal – bone marrow aspirate, bone marrow aspirate concentrate or hybrid? World J Stem Cells 2020; 12(4): 241-250
Received
2019-12-25 07:29
Peer-Review Started
2019-12-25 07:30
To Make the First Decision
Return for Revision
2020-01-19 18:48
Revised
2020-03-16 03:52
Second Decision
2020-03-19 08:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-03-22 21:23
Articles in Press
2020-03-22 21:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-04-24 07:02
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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