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Publication Name World Journal of Gastroenterology
Manuscript ID 53658
Country Japan
Category Immunology
Manuscript Type Review
Article Title Vaccine therapy for dysbiosis-related diseases
Manuscript Source Invited Manuscript
All Author List Kosuke Fujimoto and Satoshi Uematsu
Funding Agency and Grant Number
Funding Agency Grant Number
Ministry of Education, Culture, Sports, Science, and Technology of Japan (Grant-in-Aid for Early-Career Scientists) 19K17932
Corresponding Author Satoshi Uematsu, MD, PhD, Professor, Department of Immunology and Genomics, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan. uematsu.satoshi@med.osaka-cu.ac.jp
Key Words Dysbiosis; IgA; Microbiome; Mucosal immunity; Pathobiont; Vaccine
Core Tip How to control intestinal pathogenic bacteria that mediate multifactorial diseases is a major concern worldwide. There are few methods for controlling only intestinal pathogenic bacteria; therefore, we have developed a prime–boost type, next-generation mucosal vaccine, and have used it for control of bacterial intestinal diseases. This vaccine can contribute to prevention of Clostridium ramosum-mediated obesity. Thus, this approach might be useful for protecting against microbe-associated disorders of the intestine.
Citation Fujimoto K, Uematsu S. Vaccine therapy for dysbiosis-related diseases. World J Gastroenterol 2020; 26(21): 2758-2767
Received
2019-12-27 11:06
Peer-Review Started
2019-12-27 11:12
To Make the First Decision
Return for Revision
2020-02-14 17:43
Revised
2020-03-27 11:36
Second Decision
2020-05-22 09:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2020-05-23 01:04
Articles in Press
2020-05-23 01:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-06-04 07:44
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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