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Publication Name World Journal of Gastroenterology
Manuscript ID 53702
Country/Territory Germany
Category Infectious Diseases
Manuscript Type Minireviews
Article Title Innate immune recognition and modulation in hepatitis D virus infection
Manuscript Source Invited Manuscript
All Author List Stephanie Jung, Sebastian Maximilian Altstetter and Ulrike Protzer
Funding Agency and Grant Number
Funding Agency Grant Number
German Research Foundation TRR 179
Corresponding author Ulrike Protzer, MD, Director, Professor, Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, German Center for Infection Research (DZIF), Munich Partner Site, Trogerstrasse 30, Munich D-81675, Germany. protzer@helmholtz-muenchen.de
Keywords Hepatitis D virus; Hepatitis B virus; Innate immunity; Pathogen-associated molecular pattern molecules; Immune evasion; Immunosuppression
Core Tip Hepatitis D virus (HDV) is the only known human satellite virus requiring hepatitis B virus (HBV) coinfection for productive viral release. However, it was recently shown that HDV can be disseminated by viruses other than HBV in experimental setups, so it remains unexplained why HDV chose HBV as a helper virus. As HDV might possibly profit from HBV mediated immunosuppression, we first focus on recent findings on HDV recognition by the innate immune system. Later on, we summarize partially controversial data on immunomodulatory mechanisms of both, HBV and HDV.
Citation Jung S, Altstetter SM, Protzer U. Innate immune recognition and modulation in hepatitis D virus infection. World J Gastroenterol 2020; In press
Received
2019-12-29 20:11
Peer-Review Started
2019-12-29 20:12
To Make the First Decision
Return for Revision
2020-01-19 00:36
Revised
2020-03-30 13:56
Second Decision
2020-05-22 10:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-23 01:04
Articles in Press
2020-05-23 01:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jin-Lei Wang
Reviewer Code 02528812, 02528222, 00506601, 00003629, and 02450507
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 53702-Review.docx
Answering Reviewers 53702-Answering reviewers.pdf
Audio Core Tip 53702-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 53702-Conflict-of-interest statement.pdf
Copyright License Agreement 53702-Copyright license agreement.PDF
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 53702-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 53702-Language certificate.PDF
Peer-review Report 53702-Peer-review(s).pdf
Scientific Misconduct Check 53702-Scientific misconduct check.pdf
Scientific Editor Work List 53702-Scientific editor work list.pdf