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Articles in Press
4/9/2020 12:17:31 AM | Browse: 208 | Download: 376
| Category |
Geriatrics & Gerontology |
| Manuscript Type |
Review |
| Article Title |
Advances in treatment of neurodegenerative diseases: Perspectives for combination of stem cells with neurotrophic factors
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jie Wang, Wei-Wei Hu, Zhi Jiang and Mei-Jiang Feng |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Social Development Project of Jiangsu Science and Technology Department |
BE2015721 |
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| Corresponding Author |
Mei-Jiang Feng, MD, Chief Doctor, Professor, Department of Geriatrics, The Second Affiliated Hospital of Nanjing Medical University; Key Laboratory for Aging & Disease, Nanjing Medical University, Jiangjiayuan Road 121, Nanjing 210011, Jiangsu Province, China. mjfeng416@163.com |
| Key Words |
Neurodegenerative diseases; Stem cells; Brain-derived neurotrophic factor; Glial cell line-derived neurotrophic factor; Nerve growth factor; Combination therapy |
| Core Tip |
Neurodegenerative diseases are currently incurable and the therapeutic strategies have proved disappointing. Stem cells and neurotrophic factors are promising therapeutic agents, with the combination of the two being more attractive. This review focuses on the advances in such combination therapies of stem cells with neurotrophic factors in the treatment of neurodegenerative diseases. The combination of stem cells with neurotrophic factors can not only replenish the target neurons but also provide secreted neurotrophins to improve the microenvironment for nerve repair and regeneration, which might represent a new approach in the treatment of neurodegenerative diseases. |
| Citation |
Wang J, Hu WW, Jiang Z, Feng MJ. Advances in treatment of neurodegenerative diseases: Perspectives for combination of stem cells with neurotrophic factors. World J Stem Cells 2020; 12(5): 323-338 |
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Received |
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2020-02-06 11:10 |
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Peer-Review Started |
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2020-02-06 11:10 |
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To Make the First Decision |
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Return for Revision |
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2020-03-05 21:53 |
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Revised |
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2020-03-31 03:14 |
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Second Decision |
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2020-04-08 14:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-04-09 00:17 |
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Articles in Press |
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2020-04-09 00:17 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-04-20 06:09 |
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Typeset the Manuscript |
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2020-05-25 10:09 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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