Publication Name	World Journal of Clinical Cases
Manuscript ID	54187
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Colorectal adenocarcinoma patients with M1a diseases gain more clinical benefits from palliative primary tumor resection than those with M1b diseases: A propensity score matching analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Cheng-Lin Li, De-Rong Tang, Jian Ji, Bao Zang, Chen Chen and Jian-Qiang Zhao
Funding Agency and Grant Number
Corresponding Author	Jian-Qiang Zhao, MD, Doctor, Department of Thoracic Surgery, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, No. 1, West Huanghe Road, Huaian 223300, Jiangsu Province, China. shenglee6871@sina.com
Key Words	Colorectal adenocarcinoma; Palliative primary tumor resection; Distant metastasis; Propensity score matching; Surveillance Epidemiology and End Results; Overall survival
Core Tip	The National Comprehensive Cancer Network clinical practice guidelines did not recommend palliative surgery for metastatic colorectal adenocarcinoma (CRA). Using the Surveillance Epidemiology and End Results database, we found that patients with M1a diseases had a significant survival benefit compared to those with M1b diseases and patients with M1a (lung metastasis) got best long-term outcomes with median overall survival prolonged by 15 mo and with those without surgical treatment. These findings provided further evidence to support palliative surgical procedure to metastatic CRA and develop effective individualized treatment strategy.
Citation	Li CL, Tang DR, Ji J, Zang B, Chen C, Zhao JQ. Colorectal adenocarcinoma patients with M1a diseases gain more clinical benefits from palliative primary tumor resection than those with M1b diseases: A propensity score matching analysis. World J Clin Cases 2020; 8(15): 3230-3239

Received	2020-01-14 01:36
Peer-Review Started	2020-01-14 01:36
To Make the First Decision
Return for Revision	2020-04-17 06:23
Revised	2020-04-25 07:36
Second Decision	2020-06-28 10:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-06-28 23:11
Articles in Press	2020-06-28 23:11
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-07-20 00:38
Typeset the Manuscript	2020-07-30 07:44

ISSN	2307-8960 (online)
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