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Publication Name World Journal of Gastroenterology
Manuscript ID 54317
Country/Territory Switzerland
Category Surgery
Manuscript Type Systematic Reviews
Article Title Risk of malignancy in Caroli disease and syndrome: A systematic review
Manuscript Source Invited Manuscript
All Author List René Fahrner, Sandra GC Dennler and Daniel Inderbitzin
Funding Agency and Grant Number
Corresponding author René Fahrner, MD, Surgeon, Department of Surgery, Bürgerspital Solothurn, Schöngrünstrasse 42, Solothurn 4500, Switzerland. rene.fahrner@spital.so.ch
Keywords Malignancy; Caroli disease; Caroli syndrome; Tumor; Cholangiocarcinoma; Review
Core Tip Congenital intrahepatic bile duct dilatation with or without fibrosis is called Caroli syndrome or Caroli disease, respectively. We performed a systematic review of the current literature to investigate the incidence of malignant transformation, risk factors, and surgical treatment options. There were only 12 retrospective cohort studies reporting 561 patients, including 37 patients with malignancy, so an exact preoperative diagnostic work-up, risk factors and preferred surgical treatment were impossible to conclude due to lack of data. Overall survival rates after one year were low (36%), and recurrence rate was high (75%) during the observation period.
Citation Fahrner R, Dennler SG, Inderbitzin D. Risk of malignancy in Caroli disease and syndrome: A systematic review. World J Gastroenterol 2020; In press
Received
2020-01-20 11:03
Peer-Review Started
2020-01-20 11:07
To Make the First Decision
Return for Revision
2020-02-27 03:33
Revised
2020-05-15 22:10
Second Decision
2020-07-31 09:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-08-01 05:51
Articles in Press
2020-08-01 05:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Han Zhang
Reviewer Code 02519158
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 54317-Review.docx
Answering Reviewers 54317-Answering reviewers.pdf
Audio Core Tip 54317-Audio core tip.wma
Biostatistics Review Certificate 54317-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 54317-Conflict-of-interest statement.pdf
Copyright License Agreement 54317-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 54317-Language certificate.pdf
Peer-review Report 54317-Peer-review(s).pdf
Scientific Misconduct Check 54317-Scientific misconduct check.pdf
Scientific Editor Work List 54317-Scientific editor work list.pdf