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5/22/2020 5:17:30 AM | Browse: 100 | Download: 341
Publication Name World Journal of Clinical Oncology
Manuscript ID 54438
Country/Territory Poland
Category Hematology
Manuscript Type Review
Article Title Role of microRNA dysregulation in childhood acute leukemias: diagnostics, monitoring and therapeutics: A comprehensive review
Manuscript Source Invited Manuscript
All Author List Joanna Szczepanek
Funding Agency and Grant Number
Corresponding Author Joanna Szczepanek, PhD, Associate Research Scientist, Centre for Modern Interdisciplinary Technology, Nicholas Copernicus University, Wileńska 4, Toruń 87100, Poland. szczepanekj@umk.pl
Key Words miRnome; MicroRNA; Acute leukemia; Acute myeloid leukemia; Acute lymphoblastic leukemia; Biomarker
Core Tip MicroRNAs (miRNAs) are small endogenous gene expression regulators. By performing the function of oncogenes and/or tumor suppressors, they have become interesting candidates for early diagnosis, accurate classification and predictors of prognosis in the most common childhood cancers, i.e., acute leukemia. The possibility of using modulation of miRNA levels in targeted therapy is also important. Because they are noninvasive and relatively easy to determine in biological samples, miRNAs are gaining increasing attention from scientists and clinicians.
Citation Szczepanek J. Role of microRNA dysregulation in childhood acute leukemias: diagnostics, monitoring and therapeutics: A comprehensive review. World J Clin Oncol 2020; 11(6): 348-369
Received
2020-01-31 10:29
Peer-Review Started
2020-01-31 10:30
To Make the First Decision
Return for Revision
2020-04-18 22:18
Revised
2020-05-18 15:37
Second Decision
2020-05-20 10:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-22 05:17
Articles in Press
2020-05-22 05:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-05-27 18:03
Typeset the Manuscript
2020-06-23 08:34
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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