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Publication Name World Journal of Gastroenterology
Manuscript ID 54575
Country/Territory Germany
Category Gastroenterology and Hepatology
Manuscript Type Observational Study
Article Title Golimumab in real-world practice in patients with ulcerative colitis: Twelve-month results
Manuscript Source Unsolicited Manuscript
All Author List Niels Teich, Harald Grümmer, Eric Jörgensen, Thomas Liceni, Frank Holtkamp-Endemann, Tim Fischer and Susanne Hohenberger
Funding Agency and Grant Number
Funding Agency Grant Number
MSD Sharp and Dohme GmbH, Haar, Germany
Corresponding author Niels Teich, MD, Doctor, Internistische Gemeinschaftspraxis für Verdauungs-und Stoffwechselkrankheiten Leipzig und Schkeuditz, Nordstr. 21, Leipzig 04105, Germany. teich@igvs.de
Keywords Ulcerative colitis; Quality of life; Work productivity; Non-interventional study; Golimumab; Work Productivity Activity Impairment Questionnaire
Core Tip Systematic reviews indicate that ulcerative colitis (UC) causes a significant socioeconomic burden, but prospective studies are scarce. The aim of this study is to evaluate the changes in work productivity and quality of life (QoL) of UC patients in Germany treated with the human monoclonal tumor necrosis factor alpha antibody golimumab in order to assess the specific benefit of this treatment option. This prospective non-interventional study included 287 patients. Based on these data we were able to show that treatment of moderate-to-severe UC with golimumab leads to significant improvements in patient´s work productivity, daily activity and QoL over twelve months.
Citation Teich N, Grümmer H, Jörgensen E, Liceni T, Holtkamp-Endemann F, Fischer T, Hohenberger S. Golimumab in real-world practice in patients with ulcerative colitis: Twelve-month results. World J Gastroenterol 2020; In press
Received
2020-02-06 09:57
Peer-Review Started
2020-02-06 09:57
To Make the First Decision
Return for Revision
2020-03-21 23:04
Revised
2020-05-08 07:37
Second Decision
2020-05-22 10:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-23 01:01
Articles in Press
2020-05-23 01:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jia-Ping Yan
Reviewer Code 04091933, and 04091933
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 54575-Review.docx
Answering Reviewers 54575-Answering reviewers.pdf
Audio Core Tip 54575-Audio core tip.mp3
Biostatistics Review Certificate 54575-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 54575-Conflict-of-interest statement.pdf
Copyright License Agreement 54575-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 54575-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 54575-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 54575-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 54575-Language certificate.pdf
Peer-review Report 54575-Peer-review(s).pdf
Scientific Misconduct Check 54575-Scientific misconduct check.pdf
Scientific Editor Work List 54575-Scientific editor work list.pdf