BPG is committed to discovery and dissemination of knowledge
Articles in Press
5/22/2020 5:14:38 AM | Browse: 104 | Download: 203
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Interrelationship between Toll-like receptors and infection after orthotopic liver transplantation
|
Manuscript Source |
Invited Manuscript |
All Author List |
Mahmoud El-Bendary, Mustafa Naemattalah, Ahmed Yassen, Nasser Mousa, Dina Elhammady, Ahmad M Sultan and Mohamed Abdel-Wahab |
Funding Agency and Grant Number |
|
Corresponding Author |
Mahmoud El-Bendary, MD, Professor, Department of Tropical Medicine and Hepatology, Faculty of Medicine, Mansoura University, Elgomhoria Street, Mansoura 35111, Egypt. mmelbendary@gmail.com |
Key Words |
Toll like receptors; Infection; Liver transplantation; Cirrhosis; Immunity; Orthotopic |
Core Tip |
Microbial recognition by the innate immunity is accomplished by Toll-like receptors (TLRs). In spite of presence of an abundance of TLRs on the surface of the liver, gut bacteria does not elicit an inflammatory reaction in healthy individuals due to tolerance to these TLRs suggesting that the inflammatory responses seen in the liver are the result of breakdown of this tolerance. The probability of acquiring infection following hepatic transplantation is heightened due to affection of the innate immunity of the host. There is controversy about the association between genetic polymorphism of TLRs with the development of post-transplant infection. |
Citation |
El-Bendary M, Naemattalah M, Yassen A, Mousa N, Elhammady D, Sultan A, Abdel-Wahab M. Interrelationship between Toll-like receptors and infection after orthotopic liver transplantation. World J Transplant 2020; 10(6): 162-172 |
|
Received |
|
2020-02-24 00:26 |
|
Peer-Review Started |
|
2020-02-24 00:31 |
|
To Make the First Decision |
|
|
|
Return for Revision |
|
2020-04-22 21:40 |
|
Revised |
|
2020-05-09 03:21 |
|
Second Decision |
|
2020-05-21 11:46 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Company Editor-in-Chief |
|
2020-05-22 05:14 |
|
Articles in Press |
|
2020-05-22 05:14 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2020-06-15 01:18 |
ISSN |
2220-3230 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
© 2004-2024 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345