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Publication Name World Journal of Psychiatry
Manuscript ID 55073
Country/Territory Mexico
Category Psychiatry
Manuscript Type Basic Study
Article Title Serum levels of chemokines in adolescents with major depression treated with fluoxetine
Manuscript Source Invited Manuscript
All Author List Francisco Rafael de la Peña, Carlos Cruz-Fuentes, Lino Palacios, Manuel Iván Girón-Pérez, Emilio Medina-Rivero, Maria Dolores Ponce-Regalado, Samantha Alvarez-Herrera, Gilberto Pérez-Sánchez, Enrique Becerril-Villanueva, José Luis Maldonado-García, María del Carmen Jiménez-Martínez and Lenin Pavón
Funding Agency and Grant Number
Funding Agency Grant Number
Secretaria de Ciencia, Tecnología e Innovación 0048/2014
Corresponding author Lenin Pavón, PhD, Professor, Laboratory of Psychoimmunology, National Institute of Psychiatry, “Ramón de la Fuente”, Calzada México-Xochimilco 101, Colonia San Lorenzo Huipulco, Mexico City 14070, Mexico. lkuriaki@imp.edu.mx
Keywords Adolescents; Major depression; Chemokine; Fluoxetine; Interferon gamma-induced protein-10;
Core Tip Major depressive disorder affects 350 million of persons, approximately 6% of them are adolescents. This study aimed to determine the differences in circulatory levels of chemokines like eotaxin, interleukin-8, induced protein 10, monocyte chemoattractant protein-1, macrophage inflammatory protein (MIP)-1α and MIP-1β in healthy volunteers and adolescents with major depression and assess the changes induced by antidepressants consume during 8 wk of clinical follow-up, which is the minimum time to observe the therapeutic efficacy of selective serotonin reuptake inhibitors, like fluoxetine in adolescents. Our results showed a significant elevation in serum chemokine levels in adolescents with major depression despite treatment with fluoxetine and an improvement in scores of Hamilton depresión rating scale.
Citation de la Peña FR, Cruz-Fuentes C, Palacios L, Girón-Pérez MI, Medina-Rivero E, Ponce-Regalado MD, Alvarez-Herrera S, Pérez-Sánchez G, Becerril-Villanueva E, Maldonado-García JL, Jiménez-Martínez MDC, Pavón L. Serum levels of chemokines in adolescents with major depression treated with fluoxetine. World J Psychiatr 2020; In press
Received
2020-02-29 05:51
Peer-Review Started
2020-02-29 05:52
To Make the First Decision
Return for Revision
2020-04-29 21:39
Revised
2020-05-31 12:19
Second Decision
2020-06-24 08:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-06-27 20:53
Articles in Press
2020-06-27 20:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-07-05 02:24
Typeset the Manuscript
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jia-Ping Yan
Reviewer Code 02548382
Editorial Director
Journal Chief Editor
Company Chief Editor Na Ma
Language Editor Donna Fox
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 55073-Review-Filipodia.doc
Answering Reviewers 55073-Answering reviewers.pdf
Audio Core Tip 55073-Audio core tip.m4a
Biostatistics Review Certificate 55073-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 55073-Conflict-of-interest statement.pdf
Copyright License Agreement 55073-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 55073-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 55073-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 55073-Language certificate.pdf
Peer-review Report 55073-Peer-review(s).pdf
Scientific Misconduct Check 55073-Bing-Wang JL-1.jpg
Scientific Misconduct Check 55073-Bing-Yan JP-2.png
Scientific Misconduct Check 55073-Scientific misconduct check.pdf
Scientific Editor Work List 55073-Scientific editor work list.pdf