Publication Name	World Journal of Clinical Cases
Manuscript ID	55324
Country	South Korea

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Efficacy of stool multiplex polymerase chain reaction assay in adult patients with acute infectious diarrhea
Manuscript Source	Invited Manuscript
All Author List	Jae Sung Ahn, Seung In Seo, Jinseob Kim, Taewan Kim, Jin Gu Kang, Hyoung Su Kim, Woon Geon Shin, Myoung Kuk Jang and Hak Yang Kim
Funding Agency and Grant Number	Funding Agency Grant Number Kangdong Sacred Heart Hospital Fund 2017-07
Corresponding Author	Seung In Seo, MD, Assistant Professor, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, 445, Gil-dong, Kangdong-gu, Seoul KS013, South Korea. doctorssi@kdh.or.kr
Key Words	Acute infectious diarrhea; Stool multiplex polymerase chain reaction; Calprotectin; ; ;
Core Tip	Stool multiplex polymerase chain reaction (PCR) test showed improved sensitivity than conventional culture method in detecting bacterial pathogens in hospitalized patients with acute infectious diarrhea. Patients with positive stool PCR showed higher C-reactive protein expression level and colitis on sigmoidoscopy. Fecal calprotectin was found to correlate with the positivity of stool PCR, and the adjusted cut-off value of calprotectin for detecting bacterial pathogens by stool PCR was found to be 388 mg/kg.
Citation	Ahn JS, Seo SI, Kim J, Kim T, Kang JG, Kim HS, Shin WG, Jang MK, Kim HY. Efficacy of stool multiplex polymerase chain reaction assay in adult patients with acute infectious diarrhea. World J Clin Cases 2020; 8(17): 3708-3717

Received	2020-03-11 07:58
Peer-Review Started	2020-03-11 07:58
To Make the First Decision
Return for Revision	2020-05-11 06:02
Revised	2020-06-04 04:17
Second Decision	2020-07-30 09:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-08-01 05:55
Articles in Press	2020-08-01 05:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-08-26 00:31

ISSN	2307-8960 (online)
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