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Publication Name World Journal of Clinical Cases
Manuscript ID 55324
Country/Territory South Korea
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Study
Article Title Efficacy of stool multiplex polymerase chain reaction assay in adult patients with acute infectious diarrhea
Manuscript Source Invited Manuscript
All Author List Jae Sung Ahn, Seung In Seo, Jinseob Kim, Taewan Kim, Jin Gu Kang, Hyoung Su Kim, Woon Geon Shin, Myoung Kuk Jang and Hak Yang Kim
Funding Agency and Grant Number
Funding Agency Grant Number
Kangdong Sacred Heart Hospital Fund 2017-07
Corresponding author Seung In Seo, MD, Assistant Professor, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, 445, Gil-dong, Kangdong-gu, Seoul KS013, South Korea. doctorssi@kdh.or.kr
Keywords Acute infectious diarrhea; Stool multiplex polymerase chain reaction; Calprotectin
Core Tip Stool multiplex polymerase chain reaction (PCR) test showed improved sensitivity than conventional culture method in detecting bacterial pathogens in hospitalized patients with acute infectious diarrhea. Patients with positive stool PCR showed higher C-reactive protein expression level and colitis on sigmoidoscopy. Fecal calprotectin was found to correlate with the positivity of stool PCR, and the adjusted cut-off value of calprotectin for detecting bacterial pathogens by stool PCR was found to be 388 mg/kg.
Citation Ahn JS, Seo SI, Kim J, Kim T, Kang JG, Kim HS, Shin WG, Jang MK, Kim HY. Efficacy of stool multiplex polymerase chain reaction assay in adult patients with acute infectious diarrhea. World J Clin Cases 2020; In press
Received
2020-03-11 07:58
Peer-Review Started
2020-03-11 07:58
To Make the First Decision
Return for Revision
2020-05-11 06:02
Revised
2020-06-04 04:17
Second Decision
2020-07-30 09:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-08-01 05:55
Articles in Press
2020-08-01 05:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Ya-Juan Ma
Reviewer Code 00050195, and 02840182
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 55324-Review.docx
Answering Reviewers 55324-Answering reviewers.pdf
Audio Core Tip 55324-Audio core tip.mp3
Biostatistics Review Certificate 55324-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 55324-Conflict-of-interest statement.pdf
Copyright License Agreement 55324-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 55324-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 55324-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 55324-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 55324-Language certificate.pdf
Peer-review Report 55324-Peer-review(s).pdf
Scientific Misconduct Check 55324-Scientific misconduct check.pdf
Scientific Editor Work List 55324-Scientific editor work list.pdf