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Publication Name World Journal of Hepatology
Manuscript ID 55536
Country/Territory India
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title Update on diagnosis and management of sepsis in cirrhosis: Current advances
Manuscript Source Invited Manuscript
All Author List Cyriac Abby Philips, Rizwan Ahamed, Sasidharan Rajesh, Tom George, Meera Mohanan and Philip Augustine
Funding Agency and Grant Number
Corresponding author Cyriac Abby Philips, MBBS, MD, Associate Chief Physician, The Liver Unit and Monarch Liver Lab, Cochin Gastroenterology Group, Ernakulam Medical Center, 10th Floor, E.M.C Hospital, NH-Bypass, Palarivattom, Kochi 682028, Kerala, India. abbyphilips@gmail.com
Keywords Portal hypertension; Sequential organ failure assessment; Acute on chronic liver failure; Predisposition insult response organ-dysfunction model; Intensive care unit; Shock
Core Tip Advances in understanding sepsis have led to an uncomplicated and robust definition with prognostic importance. This has seen an emergence in redefining the clinical protocols for early and aggressive management of sepsis at hour one of patient presentation, identification of a novel combination of biomarkers and addressing antimicrobial resistance and identification of adjuvant therapies through deep data mining, metagenomics and machine learning-based tools for improving clinical outcomes. These advances have the potential to be extrapolated and studied in patients with cirrhosis and sepsis to improve notable catastrophic clinical outcomes seen in this unique and challenging to treat patient population.
Citation Philips CA, Ahamed R, Rajesh S, George T, Mohanan M, Augustine P. Update on diagnosis and management of sepsis in cirrhosis: Current advances. World J Hepatol 2020; In Press
Received
2020-03-22 08:55
Peer-Review Started
2020-03-22 08:58
To Make the First Decision
Return for Revision
2020-04-12 22:40
Revised
2020-05-28 17:17
Second Decision
2020-06-23 08:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-06-27 20:49
Articles in Press
2020-06-27 20:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-07-03 03:42
Typeset the Manuscript
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jia-Ping Yan
Reviewer Code 05227894, and 05086666
Editorial Director
Journal Chief Editor
Company Chief Editor Na Ma
Language Editor Donna Fox
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 55536-Review-Filipodia.docx
Answering Reviewers 55536-Answering reviewers.pdf
Audio Core Tip 55536-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 55536-Conflict-of-interest statement.pdf
Copyright License Agreement 55536-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 55536-Language certificate.pdf
Peer-review Report 55536-Peer-review(s).pdf
Scientific Misconduct Check 55536-Bing-Zhang H-1.png
Scientific Misconduct Check 55536-Bing-Yan JP-2.png
Scientific Misconduct Check 55536-Scientific misconduct check.pdf
Scientific Editor Work List 55536-Scientific editor work list.pdf