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Articles in Press
9/15/2020 11:46:48 PM | Browse: 98 | Download: 205
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Opinion Review |
| Article Title |
Role of betaine in liver disease-worth revisiting or has the die been cast?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sandeep Mukherjee |
| Funding Agency and Grant Number |
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| Corresponding Author |
Sandeep Mukherjee, FRCP (C), MBChB, Full Professor, Department of Medicine, Creighton University Medical Center, Division of Gastroenterology, Education Building, Suite 401
7710 Mercy Road, Omaha, NE 68124, United States. sandeep.mukherjee@alegent.org |
| Key Words |
Betaine; Obesity; Insulin resistance; Nonalcoholic steatohepatitis; Cirrhosis; S-adenosyl homocysteine; S-adenosyl methionine |
| Core Tip |
This article revisits the role of betaine in liver disease with a focus on nonalcoholic steatohepatitis. Although a randomized controlled trial did not report benefit over placebo, there were limitations with the study. Given the excellent safety profile and tolerance of betaine, it appears this would be an appropriate time to re-evaluate betaine for liver diseases such as nonalcoholic and alcoholic liver diseases. |
| Citation |
Mukherjee S. Role of betaine in liver disease-worth revisiting or has the die been cast? World J Gastroenterol 2020; 26(38): 5745-5748 |
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Received |
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2020-05-21 06:24 |
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Peer-Review Started |
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2020-05-21 06:25 |
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To Make the First Decision |
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Return for Revision |
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2020-05-29 03:38 |
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Revised |
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2020-08-25 09:16 |
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Second Decision |
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2020-09-15 11:22 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-09-15 23:46 |
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Articles in Press |
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2020-09-15 23:46 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-10-09 03:11 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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