Publication Name	World Journal of Gastroenterology
Manuscript ID	56086
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Current status of Helicobacter pylori eradication and risk factors for eradication failure
Manuscript Source	Unsolicited Manuscript
All Author List	Tian-Lian Yan, Jian-Guo Gao, Jing-Hua Wang, Dan Chen, Chao Lu and Cheng-Fu Xu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China (General Program) 81600447
Corresponding Author	Cheng-Fu Xu, MD, Doctor, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79, Qingchun Road, Hangzhou 310003, Zhejiang Province, China. xiaofu@zju.edu.cn
Key Words	Helicobacter pylori; Eradication; Quadruple therapy; Proton pump inhibitor; Retrospective study;
Core Tip	The Helicobacter pylori eradication rate is decreasing worldwide, and there is a lack of recent data from China. The current study of 14-d quadruple regimens in Eastern China revealed an eradication rate of 76.6%. Amoxicillin-containing regimens had the highest eradication rate in primary therapy, and amoxicillin-plus furazolidone-containing regimens showed superiority in rescue therapy. Age, prior therapy, and use of omeprazole or pantoprazole were independent risk factors of eradication failure. This study can improve choice of antibiotics and proton pump inhibitors and indicates that in clinical practice, attention should be paid to elderly patients and rescue therapy.
Citation	Yan TL, Gao JG, Wang JH, Chen D, Lu C, Xu CF. Current status of Helicobacter pylori eradication and risk factors for eradication failure. World J Gastroenterol 2020; 26(32): 4846-4856

Received	2020-04-24 09:36
Peer-Review Started	2020-04-24 09:36
To Make the First Decision
Return for Revision	2020-06-13 02:49
Revised	2020-07-18 12:13
Second Decision	2020-07-28 10:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-07-30 05:35
Articles in Press	2020-07-30 05:35
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-08-10 07:28
Typeset the Manuscript	2020-08-28 03:08

ISSN	1007-9327 (print) and 2219-2840 (online)
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