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Publication Name World Journal of Gastroenterology
Manuscript ID 56086
Country/Territory China
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Study
Article Title Current status of Helicobacter pylori eradication and risk factors of eradication failure
Manuscript Source Unsolicited Manuscript
All Author List Tian-Lian Yan, Jian-Guo Gao, Jing-Hua Wang, Dan Chen, Chao Lu and Cheng-Fu Xu
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China (General Program) 81600447
Corresponding author Cheng-Fu Xu, MD, Doctor, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79, Qingchun Road, Hangzhou 310003, Zhejiang Province, China. xiaofu@zju.edu.cn
Keywords Helicobacter pylori; Eradication; Quadruple therapy; Proton pump inhibitor; Retrospective study;
Core Tip The Helicobacter pylori eradication rate is decreasing worldwide, and there is a lack of recent data from China. The current study of 14-d quadruple regimens in Eastern China revealed an eradication rate of 76.6%. Amoxicillin-containing regimens had the highest eradication rate in primary therapy, and amoxicillin-plus furazolidone-containing regimens showed superiority in rescue therapy. Age, prior therapy, and use of omeprazole or pantoprazole were independent risk factors of eradication failure. This study can improve choice of antibiotics and proton pump inhibitors and indicates that in clinical practice, attention should be paid to elderly patients and rescue therapy.
Citation Yan TL, Gao JG, Wang JH, Chen D, Lu C, Xu CF. Current status of Helicobacter pylori eradication and risk factors of eradication failure. World J Gastroenterol 2020; In press
Received
2020-04-24 09:36
Peer-Review Started
2020-04-24 09:36
To Make the First Decision
Return for Revision
2020-06-13 02:49
Revised
2020-07-18 12:13
Second Decision
2020-07-28 10:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-07-30 05:35
Articles in Press
2020-07-30 05:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Dong-Mei Wang (Technical Editor)
Reviewer Code 03477860, and 03737603
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 56086-Review.docx
Answering Reviewers 56086-Answering reviewers.pdf
Audio Core Tip 56086-Audio core tip.mp3
Biostatistics Review Certificate 56086-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 56086-Conflict-of-interest statement.pdf
Copyright License Agreement 56086-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 56086-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 56086-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 56086-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 56086-Language certificate.pdf
Peer-review Report 56086-Peer-review(s).pdf
Scientific Misconduct Check 56086-Bing-Yan JP-1.png
Scientific Misconduct Check 56086-Scientific misconduct check.pdf
Scientific Editor Work List 56086-Scientific editor work list.pdf