Publication Name	World Journal of Gastroenterology
Manuscript ID	56550
Country	China

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Retrospective Study
Article Title	Prognostic value of pretreatment contrast-enhanced computed tomography in esophageal neuroendocrine carcinoma: A multi-center follow-up study
Manuscript Source	Unsolicited Manuscript
All Author List	Yue Zhou, Ping Hou, Kai-Ji Zha, Feng Wang, Kun Zhou, Wei He and Jian-Bo Gao
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China (General Program) 81671682 Medical Science and Technology Project of Henan Province 201602012
Corresponding Author	Jian-Bo Gao, MD, PhD, Professor, Department of Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1, Jianshe Road, Zhengzhou 450052, Henan Province, China. cjr_gaojianbo@163.com
Key Words	Esophageal neuroendocrine carcinoma; Computed tomography; Prognosis; Survival; Follow-up; Adjuvant chemotherapy
Core Tip	The occurrence of esophageal neuroendocrine carcinoma (NEC) is rare. The clinical data included in the previous prognostic models were limited and imaging data were lacking. Our results demonstrate that adjuvant chemotherapy is an independent prognostic factor of overall survival and progression-free survival. In addition, the N stage and degree of enhancement were prognostic factors of overall survival for patients with esophageal NEC. Furthermore, adjuvant chemotherapy was significantly associated with degree of enhancement, while degree of enhancement significantly correlated with esophageal wall thickness.
Citation	Zhou Y, Hou P, Zha KJ, Wang F, Zhou K, He W, Gao JB. Prognostic value of pretreatment contrast-enhanced computed tomography in esophageal neuroendocrine carcinoma: A multi-center follow-up study. World J Gastroenterol 2020; 26(31): 4680-4693

Received	2020-05-05 09:36
Peer-Review Started	2020-05-05 09:37
To Make the First Decision
Return for Revision	2020-05-15 18:24
Revised	2020-05-22 03:50
Second Decision	2020-07-29 06:58
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2020-07-30 05:33
Articles in Press	2020-07-30 05:33
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-08-03 02:45
Typeset the Manuscript	2020-08-17 00:36

ISSN	1007-9327 (print) and 2219-2840 (online)
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