Publication Name	World Journal of Gastroenterology
Manuscript ID	56587
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Etiology and management of liver injury in patients with COVID-19
Manuscript Source	Invited Manuscript
All Author List	Rui-Xu Yang, Rui-Dan Zheng and Jian-Gao Fan
Funding Agency and Grant Number	Funding Agency Grant Number National Key Research and Development Program 2017YFC0908903 National Natural Science Foundation of China (General Program) 81873565 National Natural Science Foundation of China 81900507 Hospital Funded Clinical Research, Xinhua hospital Affiliated to Shanghai Jiao Tong University school of medicine 17CSK04
Corresponding Author	Jian-Gao Fan, MD, PhD, Chief Doctor, Professor, Center for Fatty Liver, Department of Gastroenterology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai Key Lab of Pediatric Gastroenterology and Nutrition, No. 1665 Kongjiang Road, Shanghai 200092, China. fanjiangao@xinhuamed.com.cn
Key Words	COVID-19; SARS‐CoV‐2; Coronavirus; Liver injury; Function test; Liver
Core Tip	The pandemic of coronavirus disease 2019 (COVID-19) has aroused a global threat to human health. With the deepening of related research, it was found that in addition to respiratory symptoms, digestive involvements and liver injury were reported in COVID-19. Viral immunologic injury, drug-induced liver injury, secondary liver injury induced by systemic inflammatory response or hypoxia, and the exacerbation of pre-existing liver disease might be the etiologic factors of liver injury in COVID-19. Health workers need to pay attention to the management of pre-existing liver disease, monitor the liver function and strengthen supportive treatment and reduce the chance of drug-induced liver injury with COVID-19.
Citation	Yang RX, Zheng RD, Fan JG. Etiology and management of liver injury in patients with COVID-19. World J Gastroenterol 2020; 26(32): 4753-4762

Received	2020-05-08 15:32
Peer-Review Started	2020-05-08 15:32
To Make the First Decision
Return for Revision	2020-05-15 05:14
Revised	2020-05-23 13:47
Second Decision	2020-08-12 11:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-08-12 19:03
Articles in Press	2020-08-12 19:03
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-08-17 13:53
Typeset the Manuscript	2020-08-28 03:11

ISSN	1007-9327 (print) and 2219-2840 (online)
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