Publication Name	World Journal of Gastroenterology
Manuscript ID	56692
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Immune infiltration-associated serum amyloid A1 predicts favorable prognosis for hepatocellular carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Wei Zhang, Hui-Fang Kong, Xu-Dong Gao, Zheng Dong, Ying Lu, Jia-Gan Huang, Hong Li and Yong-Ping Yang
Funding Agency and Grant Number	Funding Agency Grant Number Guizhou Provincial Natural Science Foundation 2020-1Y299
Corresponding Author	Yong-Ping Yang, MD, Chief Doctor, Center for Diagnosis and Research of Liver Tumor, Fifth Medical Center of People's Liberation Army General Hospital, No. 100 West Sihuan Road, Fengtai District, Beijing 100191, China. yyp1542@163.com
Key Words	Serum amyloid A1; Hepatocellular carcinoma; Low expression; Prognosis; Hepatitis; Immune pathways
Core Tip	In this study, we identified the downregulation of serum amyloid A1 (SAA1) in the hepatocellular carcinoma (HCC), and SAA1 expression could predict the favorable prognosis for HCC patients, especially for those patients without hepatitis virus infection. And SAA1 expression was closely associated with anti-tumor immunity signaling pathways. We also identified two signature genes associated with SAA1, performing the favorable prognosis function for HCC patients.
Citation	Zhang W, Kong HF, Gao XD, Dong Z, Lu Y, Huang JG, Li H, Yang YP. Immune infiltration-associated serum amyloid A1 predicts favorable prognosis for hepatocellular carcinoma. World J Gastroenterol 2020; 26(35): 5287-5301

Received	2020-05-10 08:28
Peer-Review Started	2020-05-10 08:28
To Make the First Decision
Return for Revision	2020-07-29 05:17
Revised	2020-08-03 03:07
Second Decision	2020-08-12 11:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-08-12 19:02
Articles in Press	2020-08-12 19:02
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-08-21 13:54
Typeset the Manuscript	2020-09-15 01:08

ISSN	1007-9327 (print) and 2219-2840 (online)
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