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11/21/2020 5:52:03 AM | Browse: 38 | Download: 12
Publication Name World Journal of Clinical Cases
Manuscript ID 56814
Country/Territory Japan
Category Infectious Diseases
Manuscript Type Editorial
Article Title Understanding the immunopathogenesis of COVID-19: Its implication for therapeutic strategy
Manuscript Source Invited Manuscript
All Author List Yukihiro Shimizu
Funding Agency and Grant Number
Corresponding author Yukihiro Shimizu, MD, PhD, Director, Doctor, Gastroenterology Center, Nanto Municipal Hospital, 938 Inami, Nanto 932-0211, Toyama, Japan. rsf14240@nifty.com
Key Words COVID-19; SARS-CoV-2; Immune response; Antibody; Viral kinetics; Treatment
Core Tip Since the coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), the core therapeutic strategy should be aimed at the eradication of the virus. Unfortunately, there have been no antiviral drugs proven to be effective for this viral infection. The pathogenesis of SARS-CoV-2 is formed by the interaction between the viral infection and the immune response to the virus, and the various clinical features observed in patients with COVID-19 could be due to differences in host immune responses. Moreover, therapeutic strategies should be based on both viral kinetics and the immune response. This editorial summarizes current understanding about immune responses in patients infected with SARS-CoV-2 and provides clues to therapeutic strategies based on this information.
Citation Shimizu Y. Understanding the immunopathogenesis of COVID-19: Its implication for therapeutic strategy. World J Clin Cases 2020; In press
Received
2020-05-15 08:45
Peer-Review Started
2020-05-15 08:46
To Make the First Decision
Return for Revision
2020-11-03 06:00
Revised
2020-11-12 11:28
Second Decision
2020-11-19 08:34
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-11-21 05:52
Articles in Press
2020-11-21 05:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Xi-Fang Chen (Part-Time Editor)
Reviewer Code 02916655, and 02916655
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 56814_Auto_Edited.docx
Answering Reviewers 56814-Answering reviewers.pdf
Audio Core Tip 56814-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 56814-Conflict-of-interest statement.pdf
Copyright License Agreement 56814-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 56814-Language certificate.pdf
Peer-review Report 56814-Peer-review(s).pdf
Scientific Misconduct Check 56814-Bing-Chen XF-2.png
Scientific Misconduct Check 56814-Bing-Ma YJ-1.jpg
Scientific Misconduct Check 56814-Scientific misconduct check.pdf
Scientific Editor Work List 56814-Scientific editor work list.pdf