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8/1/2020 5:50:27 AM | Browse: 152 | Download: 544
Publication Name World Journal of Gastroenterology
Manuscript ID 57106
Country China
Category Oncology
Manuscript Type Retrospective Cohort Study
Article Title Impact of interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer patients
Manuscript Source Unsolicited Manuscript
All Author List Shi-Wen Mei, Zheng Liu, Fang-Ze Wei, Jia-Nan Chen, Zhi-Jie Wang, Hai-Yu Shen, Juan Li, Fu-Qiang Zhao, Wei Pei, Zheng Wang, Xi-Shan Wang and Qian Liu
Funding Agency and Grant Number
Funding Agency Grant Number
the Medicine and Health Technology Innovation Project of Chinese Academy of Medical Sciences 2017-12M-1-006
National Key Research and Development Plan "Research on Prevention and Control of Major Chronic Non-Communicable Diseases" 2019YFC1315705
Corresponding Author Qian Liu, MD, Chief Doctor, Professor, Surgeon, Department of Colorectal Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. fcwpumch@163.com
Key Words Interval time; Advanced rectal cancer; Disease-free survival; Pathologic complete response; Neoadjuvant therapy; Surgery
Core Tip The time interval between neoadjuvant therapy and surgery is an underlying debate. This study mainly analyzed the effect of prolonging the time interval to surgery after neoadjuvant therapy on pathologic response and disease-free survival. Our study concluded that time interval > 9 wk will result in better prognosis and oncologic outcomes than time interval ≤ 9 wk. In practice, we should prolong the time interval to obtain favorable outcomes in advanced rectal cancer after neoadjuvant therapy.
Citation Mei SW, Liu Z, Wei FZ, Chen JN, Wang ZJ, Shen HY, Li J, Zhao FQ, Pei W, Wang Z, Wang XS, Liu Q. Impact of interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer patients. World J Gastroenterol 2020; 26(31): 4624-4638
Received
2020-05-26 09:03
Peer-Review Started
2020-05-26 09:04
To Make the First Decision
Return for Revision
2020-06-04 18:05
Revised
2020-06-07 15:40
Second Decision
2020-07-31 09:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-08-01 05:50
Articles in Press
2020-08-01 05:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-08-10 07:17
Typeset the Manuscript
2020-08-20 00:20
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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