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Publication Name World Journal of Hepatology
Manuscript ID 57138
Country/Territory Saudi Arabia
Category Gastroenterology and Hepatology
Manuscript Type Meta-Analysis
Article Title Efficacy and safety of once daily tacrolimus compared to twice daily tacrolimus after liver transplantation
Manuscript Source Unsolicited Manuscript
All Author List Khalid Ibrahim Bzeizi, Ali Albenmousa, Abdulhaleem Mohamed Shawkat, Zidan Ahmed, Saleh Alabbad, Waleed Alhamoudi, Roberto Troisi and Deiter Broering
Funding Agency and Grant Number
Corresponding Author Khalid Ibrahim Bzeizi, FRCP, Doctor, Department of Liver Transplantation, King Faisal Specialist Hospital and Research Center, Zahrawi Street, Al Maather, Riyadh 12713, Saudi Arabia. kbzeizi@kfshrc.edu.sa
Key Words Prolonged release; Tacrolimus; Liver transplantation; Graft rejection; Renal impairment; FK level
Core Tip Tacrolimus, a calcineurin inhibitor is an important component of the immunosuppressive regimens post liver transplantation. Compliance to immunosuppression treatment generally is important and non-adherence is a major risk factor of graft rejection and loss. Compliance to medication declines over the course of time in patients after liver transplantation due to several factors and this contributes to about 20% of late acute rejection. The efficacy of once daily tacrolimus regimens has been reported in many studies and this systematic review/meta-analysis confirmed the evidence of comparable efficacy and safety of prolonged release tacrolimus to the twice daily immediate release formulation.
Citation Bzeizi KI, Albenmousa A, Shawkat AM, Ahmed Z, Alabbad S, Alhamoudi W, Troisi R, Broering D. Efficacy and safety of once daily tacrolimus compared to twice daily tacrolimus after liver transplantation. World J Hepatol 2021; In press
Received
2020-11-05 12:37
Peer-Review Started
2020-11-05 12:37
To Make the First Decision
Return for Revision
2020-11-30 19:16
Revised
2021-01-04 17:13
Second Decision
2021-02-06 07:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-02-18 20:01
Articles in Press
2021-02-18 20:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Le Zhang
Reviewer Code 00053709
Editorial Director
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 57138_Auto_Edited_LM.docx
Answering Reviewers 57138-Answering reviewers.pdf
Audio Core Tip 57138-Audio core tip.m4a
Biostatistics Review Certificate 57138-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 57138-Conflict-of-interest statement.pdf
Copyright License Agreement 57138-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 57138-Language certificate.pdf
Peer-review Report 57138-Peer-review(s).pdf
Scientific Misconduct Check 57138-Scientific misconduct check.pdf
Scientific Editor Work List 57138-Scientific editor work list.pdf