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7/30/2020 5:14:53 AM | Browse: 39 | Download: 19
Publication Name World Journal of Gastroenterology
Manuscript ID 57275
Country/Territory China
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Feasibility and efficacy evaluation of metallic biliary stents eluting gemcitabine and cisplatin for extrahepatic cholangiocarcinoma
Manuscript Source Unsolicited Manuscript
All Author List Jing-Bo Xiao, Jun-Yong Weng, Yang-Yang Hu, Gui-Long Deng and Xin-Jian Wan
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81470904
Science and Technology Development Funds of Shanghai of China 16411952400
National Natural Science Foundation of China 81870452
Corresponding author Xin-Jian Wan, MD, Chief Doctor, Department of Gastroenterology & Shanghai Key Laboratory of Pancreatic Diseases, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, No. 650, Xinsongjiang Road, Shanghai 201620, China. xinjian_wan_shsl@163.com
Keywords Extrahepatic cholangiocarcinoma; Drug-eluting stent; Local chemotherapy; Gemcitabine; Cisplatin; Biliary obstruction
Core Tip Drug-eluting stent is a relatively new therapeutic concept for malignant biliary obstructions; however, there have only been limited studies reported and all of them were single-drug-loaded type with a simple design, also lack complete, serial in vitro and in vivo study. Our study was the first trial to apply dual chemotherapeutic medications to Drug-eluting stent with several improvements in the design compared to previous ones for the palliative therapy of extrahepatic cholangiocarcinoma with relatively complete pre-clinical evaluation, and our results indicated this brand-new stent could be a promising alternative to realize dual functions of biliary drainage and local chemotherapy.
Citation Xiao JB, Weng JY, Hu YY, Deng GL, Wan XJ. Feasibility and efficacy evaluation of metallic biliary stents eluting gemcitabine and cisplatin for extrahepatic cholangiocarcinoma. World J Gastroenterol 2020; In press
Received
2020-06-03 23:09
Peer-Review Started
2020-06-03 23:09
To Make the First Decision
Return for Revision
2020-06-18 04:36
Revised
2020-06-30 21:27
Second Decision
2020-07-28 12:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-07-30 05:14
Articles in Press
2020-07-30 05:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-08-08 03:21
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access his article is an open-access article that was selected by an inhouse editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Le Zhang
Reviewer Code 02572474, and 02954069
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor Jing-Yun Ma
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 57275-Review-Ma JY.docx
Answering Reviewers 57275-Answering reviewers.pdf
Audio Core Tip 57275-Audio core tip.mp3
Biostatistics Review Certificate 57275-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 57275-Conflict-of-interest statement.pdf
Copyright License Agreement 57275-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 57275-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 57275-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 57275-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 57275-Language certificate.pdf
Supplementary Material 57275-Supplementary material.pdf
Peer-review Report 57275-Peer-review(s).pdf
Scientific Misconduct Check 57275-Bing-Yan JP-1.png
Scientific Misconduct Check 57275-Scientific misconduct check.pdf
Scientific Editor Work List 57275-Scientific editor work list.pdf