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Publication Name World Journal of Gastroenterology
Manuscript ID 57352
Country/Territory China
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title Current understanding of the metabolism of micronutrients in chronic alcoholic liver disease: A review
Manuscript Source Unsolicited Manuscript
All Author List Jing Wu and Qing-Hua Meng
Funding Agency and Grant Number
Funding Agency Grant Number
Municipal Natural Science Foundation of Beijing of China 7192085
Corresponding author Qing-Hua Meng, MD, PhD, Chief Doctor, Professor, Department of Critical Care Medicine of Liver Disease, Beijing You-An Hospital, Capital Medical University, No.8 Xitoutiao, Youanmen Wai, Fengtai District, Beijing 100069, China. meng_qh@126.com
Keywords Alcoholic liver disease; Metabolism; Trace elements; Vitamins; Malnutrition; Oxidative stress
Core Tip Perturbation of micronutrients has been broadly reported to be a common characteristic of patients with Alcoholic liver disease (ALD). In the current study, we provide a review of recent studies that investigated the micronutrients imbalance in patients with ALD with a focus on zinc, iron, copper, magnesium, selenium, vitamin D and vitamin E, as well as dissect how disturbance in micronutrients relates to the pathophysiology of ALD. More importantly, we also highlight several challenges in terms of low sample size, study design discrepancies, sample heterogeneity across studies, and use of machine learning approaches.
Citation Wu J, Meng QH. Current understanding of the metabolism of micronutrients in chronic alcoholic liver disease. World J Gastroenterol 2020; In press
Received
2020-06-04 13:55
Peer-Review Started
2020-06-04 13:57
To Make the First Decision
Return for Revision
2020-06-18 04:33
Revised
2020-06-22 10:32
Second Decision
2020-07-29 10:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-07-30 05:11
Articles in Press
2020-07-30 05:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Le Zhang
Reviewer Code 03293832, and 03293832
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Electronic Editor
Responsible Electronic Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 57352-Review.docx
Answering Reviewers 57352-Answering reviewers.pdf
Audio Core Tip 57352-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 57352-Conflict-of-interest statement.pdf
Copyright License Agreement 57352-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 57352-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 57352-Language certificate.pdf
Peer-review Report 57352-Peer-review(s).pdf
Scientific Misconduct Check 57352-Bing-Yan JP-1.png
Scientific Misconduct Check 57352-Scientific misconduct check.pdf
Scientific Editor Work List 57352-Scientific editor work list.pdf