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Publication Name World Journal of Gastroenterology
Manuscript ID 57608
Country/Territory Israel
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Study
Article Title Older age, longer procedures and tandem endoscopic-ultrasound as risk factors for post-endoscopic retrograde cholangiopancreatography bacteremia
Manuscript Source Unsolicited Manuscript
All Author List Liat Deutsch, Shay Matalon, Adam Phillips, Moshe Leshno, Oren Shibolet and Erwin Santo
Funding Agency and Grant Number
Corresponding author Erwin Santo, MD, Chief Doctor, Chief Physician, Doctor, Department of Gastroenterology and Liver Diseases, Tel Aviv Medical Center, Affiliated with Sackler School of Medicine, Tel Aviv University, 6 weizmann st, Tel Aviv 6423906, ISRAEL, Israel. erwins@tlvmc.gov.il
Key Words Endoscopic retrograde cholangiopancreatography; Bacteremia; Tandem-procedures; Fine needle aspiration; Antibiotic prophylaxis; Biliary drainage
Core Tip Clinically significant post-endoscopic retrograde cholangiopancreatography (ERCP) bacteremia (PEB) occurs in up to 5% of cases, while antibiotic prophylaxis is recommended when an ERCP is unlikely to achieve complete biliary drainage. Our aim was to identify novel risk factors for PEB and evaluate appropriateness of antibiotic prophylaxis. This retrospective cohort study included 626 ERCPs while PEB prevalence was 3.7%. Antibiotic prophylaxis was administrated in 22.2% of cases but was indicated in 7%. Independent risk factors for PEB were: Age ≥ 75 years, Tandem-EUS/ERCP with FNA and ERCP duration ≥ 60 min (P < 0.005). These novel risk factors should be further evaluated as indications for prophylactic antibiotic treatment before ERCP.
Citation Deutsch L, Matalon S, Phillips A, Leshno M, Shibolet O, Santo E. Older age, longer procedures and tandem endoscopic-ultrasound as risk factors for post-endoscopic retrograde cholangiopancreatography bacteremia. World J Gastroenterol 2020; In press
Received
2020-06-18 07:05
Peer-Review Started
2020-06-18 07:06
To Make the First Decision
Return for Revision
2020-07-28 22:36
Revised
2020-08-16 12:19
Second Decision
2020-09-15 12:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-09-15 23:34
Articles in Press
2020-09-15 23:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Han Zhang (Part-Time Editor)
Reviewer Code 05190195, and 02536337
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 57608-Review.docx
Answering Reviewers 57608-Answering reviewers.pdf
Audio Core Tip 57608-Audio core tip.m4a
Biostatistics Review Certificate 57608-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 57608-Conflict-of-interest statement.pdf
Copyright License Agreement 57608-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 57608-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 57608-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 57608-Language certificate.pdf
Supplementary Material 57608-Supplementary material.pdf
Peer-review Report 57608-Peer-review(s).pdf
Scientific Misconduct Check 57608-Bing-Yan JP-1.png
Scientific Misconduct Check 57608-Scientific misconduct check.pdf
Scientific Editor Work List 57608-Scientific editor work list.pdf