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Publication Name World Journal of Gastroenterology
Manuscript ID 57608
Country/Territory Israel
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Older age, longer procedures and tandem endoscopic-ultrasound as risk factors for post-endoscopic retrograde cholangiopancreatography bacteremia
Manuscript Source Unsolicited Manuscript
All Author List Liat Deutsch, Shay Matalon, Adam Phillips, Moshe Leshno, Oren Shibolet and Erwin Santo
Funding Agency and Grant Number
Corresponding Author Erwin Santo, MD, Chief Doctor, Chief Physician, Doctor, Department of Gastroenterology and Liver Diseases, Tel Aviv Medical Center, Affiliated with Sackler School of Medicine, Tel Aviv University, 6 weizmann st, Tel Aviv 6423906, ISRAEL, Israel. erwins@tlvmc.gov.il
Key Words Endoscopic retrograde cholangiopancreatography; Bacteremia; Tandem-procedures; Fine needle aspiration; Antibiotic prophylaxis; Biliary drainage
Core Tip Clinically significant post-endoscopic retrograde cholangiopancreatography (ERCP) bacteremia (PEB) occurs in up to 5% of cases, while antibiotic prophylaxis is recommended when an ERCP is unlikely to achieve complete biliary drainage. Our aim was to identify novel risk factors for PEB and evaluate appropriateness of antibiotic prophylaxis. This retrospective cohort study included 626 ERCPs while PEB prevalence was 3.7%. Antibiotic prophylaxis was administrated in 22.2% of cases but was indicated in 7%. Independent risk factors for PEB were: Age ≥ 75 years, Tandem-EUS/ERCP with FNA and ERCP duration ≥ 60 min (P < 0.005). These novel risk factors should be further evaluated as indications for prophylactic antibiotic treatment before ERCP.
Citation Deutsch L, Matalon S, Phillips A, Leshno M, Shibolet O, Santo E. Older age, longer procedures and tandem endoscopic-ultrasound as risk factors for post-endoscopic retrograde cholangiopancreatography bacteremia. World J Gastroenterol 2020; 26(41): 6402-6413
Received
2020-06-18 07:05
Peer-Review Started
2020-06-18 07:06
To Make the First Decision
Return for Revision
2020-07-28 22:36
Revised
2020-08-16 12:19
Second Decision
2020-09-15 12:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-09-15 23:34
Articles in Press
2020-09-15 23:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-11-05 01:44
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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